[159名患有死性软组织感染的患者的临床特征和败血症相关因素]
Hongmin Luo1, Xiaoyan Wang, Xu Mu
1Department of Burns and Wound Repair Surgery, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou 510080, China. Corresponding author: Lai Wen,
Zhonghua wei zhong bing ji jiu yi xue
|October 28, 2025
概括
末性软组织感染 (NSTI) 患者经常出现并发症和延迟治疗. 冠心病,C反应蛋白和总胆红素是这些患者败血症的关键预测因素.
科学领域:
- 传染性疾病 传染性疾病
- 关键护理医学 关键护理医学
- 手术感染 手术感染
背景情况:
- 末性软组织感染 (NSTI) 是一种严重的疾病,患病率和死亡率很高.
- 早期识别诸如败血症等并发症的危险因素对于改善患者的治疗结果至关重要.
研究的目的:
- 为了研究NSTI患者的临床特征.
- 确定与NSTI患者败血症发展相关的因素.
主要方法:
- 一个回顾性病例系列分析了159名NSTI患者的临床数据.
- 后勤回归和ROC曲线分析确定了败血症的预测因素.
主要成果:
- 常见的并发病包括糖尿病和高血压;下肢是最常见的感染部位.
- 败血症是最常见的并发症 (41.51%).
- 冠状动脉心脏病,高C反应蛋白和总胆红素是败血症的独立预测因子,AUC总值为0.799.
结论:
- NSTI患者的临床特征表现出有助于风险评估的模式.
- 冠心病,C-反应蛋白和总胆红素是NSTI患者败血症发展的重要独立预测因素,使得有针对性的干预措施成为可能.
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