肠道环境的重金属排毒:益生菌补充剂的潜在应用和挑战
Banasree Bhowmik1, Md Nur Hossain1, Sadia Afrin1
1Institute of Food Science and Technology, Bangladesh Council of Scientific and Industrial Research, Dhaka, Bangladesh.
Journal of the science of food and agriculture
|October 28, 2025
概括
益生菌外聚糖 (EPS) 可以减少肠道微生物群中的重金属毒性. 这项研究探讨了EPS如何帮助重金属的生物吸收,保护肠道健康免受环境污染物的影响.
科学领域:
- 微生物学与环境科学 微生物学与环境科学
- 人类肠道微生物组研究研究
- 生物修复和重金属毒理学
背景情况:
- 人类微生物组在宿主健康和新陈代谢中起着至关重要的作用.
- 和等重金属会破坏肠道微生物群的平衡,导致氧化损伤和健康问题.
- 益生菌微生物可以改善胃肠道健康,但它们的有效性可能会受到HM暴露的影响.
研究的目的:
- 讨论益生菌补充在重金属生物吸收中的作用.
- 提高人们对重金属对人类新陈代谢和肠道健康的健康影响的认识.
- 探索外聚糖 (EPS) 在减轻HM毒性的潜力.
主要方法:
- 对益生菌外聚糖 (EPS) 和重金属 (HM) 相互作用的现有文献的审查.
- 讨论HM毒性机制,包括活性氧物种 (ROS) 生成和细胞损伤.
- 分析EPS生物聚合物对HM结合和去除的特性.
主要成果:
- 益生菌中的外聚糖 (EPS) 可以有效地降低重金属的毒性和流动性.
- EPS生物聚合物与金属离子结合,防止对生物体的有害影响.
- EPS增强益生菌微生物的生长和活性,有助于生物修复.
结论:
- 益生菌外聚糖在减轻肠道微生物群中的重金属污染方面表现有前途.
- 需要进一步的研究,以了解细菌机制和细胞表面形态,以获得最佳的HM吸收.
- 了解这些相互作用对于保护人类肠道健康免受环境重金属暴露至关重要.
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