在三透管边缘到边缘修复后,右心室功能的适应
Sara Bombace1, Sebastian Rosch1, Anne R Schöber1
1Department of Cardiology, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany.
ESC heart failure
|October 28, 2025
概括
三管横导管边缘到边缘修复 (T-TEER) 对患者的右心室喷射率 (RVEF) 有不同的影响. 在T-TEER后的RVEF增加是罕见的,并且与三管吐恶化和较差的结局有关.
科学领域:
- 心脏病学 心脏病学
- 干预心脏病学 干预心脏病学
- 心脏成像 - - 心脏成像
背景情况:
- 三管横导管边缘到边缘修复 (T-TEER) 越来越多地用于严重的三管吐.
- 对于T-TEER对右心室 (RV) 重塑和功能的影响尚未完全理解.
研究的目的:
- 为了研究T-TEER后右心室喷射率 (RVEF) 的变化.
- 为了确定在T-TEER之后RVEF变化的预后意义.
主要方法:
- 对69名接受T-TEER手术的患者进行前后心脏磁共振成像 (CMR) 的回顾性分析.
- 根据RVEF变化分类的患者:降低 (≤-5%),稳定 (-4%至4%) 或增加 (≥5%).
- 主要结局:综合所有原因死亡率或心力衰竭住院治疗.
主要成果:
- 在46%的患者中,RVEF下降,在39%的患者中保持稳定,在15%的患者中增加.
- 增加的RVEF与较低的基线RVEF和较差的RV到肺动脉 (RV-PA) 合有关.
- 患有RVEF增加的患者经历了三腹吐 (TR) 的恶化,并且发生事件率最高 (死亡率/心力衰竭住院).
结论:
- 对T-TEER的RV反应是异质的,受基线RV功能,RV-PA合和TR进展的影响.
- 少数患者在T-TEER后显示RVEF增加,与不良结果相关.
- 在T-TEER之后的RVEF变化提供了重要的预后信息.
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