急性咖啡因摄入对COPD患者耐力表现和心脏自主调节的影响
B M Costa1, A Ferreira Junior1, G Ferreira1
1Department of Physical Education, State University of Ponta Grossa (UEPG), Ponta Grossa, PR, Brazil.
Journal of the American Nutrition Association
|October 28, 2025
概括
咖啡因摄入改善了慢性阻塞性肺病 (COPD) 患者的耐力运动能力. 虽然咖啡因在运动期间没有影响心率,但咖啡因增加了疲劳和初始心率恢复的时间.
科学领域:
- 运动生理学 运动生理学
- 肺部康复治疗 肺部康复治疗
- 营养科学 营养科学
背景情况:
- 慢性阻塞性肺病 (COPD) 显著影响运动能力和生活质量.
- 了解像咖啡因这样的人体营养助剂可以帮助优化COPD患者的运动表现.
- 心脏自主功能在运动耐受性和恢复中起着至关重要的作用.
研究的目的:
- 评估急性咖啡因 (CAF) 摄入对COPD患者运动表现和心脏自主调节的影响.
- 为了确定CAF是否影响心率 (HR) 和持续负荷运动测试期间疲劳的时间.
- 评估CAF对心率变化 (HRV) 的影响,作为心脏自主调节的指标.
主要方法:
- 一项随机,双盲,安慰剂控制的交叉研究,涉及11名COPD患者.
- 参与者在摄入CAF (5 mg/kg) 或安慰剂 (PLA) 后进行了常量负荷运动测试.
- 在运动和恢复期间,对HR和HRV进行了持续的节拍监测.
主要成果:
- 与安慰剂相比,摄入咖啡因显著增加了疲劳的时间 (p=0.04).
- 在CAF和PLA条件之间没有观察到运动期间HR的显著差异.
- 咖啡因降低了运动后60秒HR恢复的幅度 (p=0.02),但没有改变HRV指数.
结论:
- 急性咖啡因摄入增加了COPD患者的耐力运动表现,通过增加疲劳的时间.
- 在这个人群中,咖啡因似乎不会在运动期间或之后对心脏自主调节产生负面影响.
- 咖啡因可能是一种安全有效的人体工程学辅助剂,用于改善COPD患者的运动能力.
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