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Updated: Jan 13, 2026

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基于LSTM对使用ADME和物理化学性能的静脉注射小分子药物的人类PK配置文件和参数的预测

Pingyao Luo1,2, Rong Chen1,2, Zhisong Wu2

  • 1Department of Pharmacy Administration and Clinical Pharmacy, School of Pharmaceutical Sciences, Peking University, Beijing, China.

CPT: pharmacometrics & systems pharmacology
|October 28, 2025
PubMed
概括

本研究引入了一种使用长短期记忆 (LSTM) 预测人类药理动力学 (PK) 度-时间概况的机器学习模型. 该模型有效地预测了静脉注射剂量的PK行为,有助于药物开发中的化合物选择.

关键词:
度-时间预测长期短期记忆 (LSTM) 网络.机器学习是机器学习.药物动力学 药物动力学

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