使用功能近红外光谱检测重症监护室的意识
Karnig Kazazian1,2, Jack de Jeu1,3, Androu Abdalmalak2
1Western Institute of Neuroscience, Western University, London, ON, Canada.
Annals of neurology
|October 28, 2025
概括
功能近红外光谱检测到25%的脑损伤患者无法执行命令的隐藏意识. 这种神经成像技术可以通过揭示隐藏的意识来改善护理决策.
科学领域:
- 神经科学是一个神经科学.
- 关键护理医学 关键护理医学
- 医疗成像医学成像
背景情况:
- 评估患有急性脑损伤的重症患者的意识对于指导治疗决策至关重要.
- 床边神经学检查可能无法检测到一些患者的意识.
- 隐蔽意识是指通过行为反应不显而易见的保存意识.
研究的目的:
- 调查功能近红外光谱学 (fNIRS) 在识别隐藏意识方面的实用性.
- 在急性脑损伤患者中评估大脑活动,这些患者不能遵循命令.
主要方法:
- 一项针对32名急性脑损伤重症监护病房患者的前性,横截面研究.
- 患者使用昏迷恢复尺度-修订进行评估,并发现无法执行命令.
- fNIRS被用来检测在心理图像任务 (想象打网球) 期间的大脑活动.
主要成果:
- 在32名患者中,有8名患者 (25%) 通过在心理图像任务中调节大脑活动来表现出隐藏的意识.
- 在隐蔽意识和3个月的功能结果之间没有发现任何关联 (格拉斯哥结果扩展).
结论:
- fNIRS成功检测到25%缺乏行为指挥的患者的保持意识.
- 像fNIRS这样的先进神经成像技术可能会提高重症监护中的临床评估.
- 准确的意识评估对于在严重脑损伤中做出明智的护理目标决策至关重要.
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