40-69岁的土耳其女性的缩短MRI查与密集的乳房:一个潜在的可行性研究
Inci Kizildag Yirgin1, Neslihan Cabioglu2, Memduh Dursun3
1Department of Radiology. Oncology Institute, Istanbul University, Istanbul, Turkey.
缩短协议 (AP) 乳房MRI查在女性有密集的乳房没有显示任何额外的癌症,但导致错误的阳性. 需要进一步的多中心研究来评估AP-MRI.
科学领域:
- 放射学 放射学是一门学科.
- 在瘤学瘤学.
- 公共卫生 公共卫生
背景情况:
- 密集的乳房增加了乳腺癌的风险.
- 查性乳房扫描可能在密集的乳房有局限性.
- 磁共振成像 (MRI) 为检测乳腺癌提供了更高的灵敏度.
研究的目的:
- 评估缩写协议 (AP) 乳腺MRI查在一个中等收入国家的查计划中,在乳腺密度较高的女性中的可行性.
- 评估AP-MRI在这个人群中的诊断性能和挑战.
- 为了确定AP-MRI是否可以有效地补充乳房扫描,用于早期发现乳腺癌.
主要方法:
- 对238名乳腺密度高的女性 (C/D型) 进行前性研究,接受AP-MRI查.
- AP-MRI 协议包括动态对比增强序列和特定序列 (T1W,T2W-fat sat).
- 参考标准结合了病理学结果和2年的乳房造影随访.
主要成果:
- 84.4%的扫描显示正常/良性发现 (BIRADS-1/2).
- 10.5%是BI-RADS-3,在2年内没有进展.
- 5%是BI-RADS-4,但在进一步评估后,活检显示没有恶性瘤.
结论:
- 在这个队列中,补充AP-MRI查没有检测到其他癌症.
- AP-MRI与假阳性相关,可能导致过度诊断和不必要的活检.
- 需要进行更大规模的多中心研究来确定AP-MRI的作用和最佳整合到乳腺癌查计划中.
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