炎症性肠病患者的睡眠质量和相关因素:一个横截面研究
Mehrnaz Asgharnezhad1, Saman Maroufizadeh2, Adele Isanazar3
1Epidemiology, Gastrointestinal and Liver Diseases Research Center, Guilan University of Medical Sciences, Rasht, Iran.
Sleep & breathing = Schlaf & Atmung
|October 28, 2025
概括
在炎症性肠病 (IBD) 中,睡眠质量与抑郁症和并发症比疾病活动更相关. 常规的心理健康查对于管理IBD患者的睡眠问题至关重要.
科学领域:
- 胃肠病学 胃肠病学
- 睡眠医学 睡眠医学
- 精神病学是一个精神病学.
背景情况:
- 稳定的睡眠-觉醒周期对于免疫功能至关重要.
- 炎症性肠病 (IBD) 经常导致睡眠障碍和疲劳,可能会影响疾病的进展.
- 了解影响IBD患者睡眠的因素对于有效管理至关重要.
研究的目的:
- 研究诊断为IBD的患者的睡眠质量和相关因素之间的关系.
- 为了确定IBD人口中睡眠障碍的关键贡献者.
主要方法:
- 一项涉及伊朗307名成年IBD患者 (性结肠炎和克罗恩病) 的横截面研究.
- 通过匹兹堡睡眠质量指数 (PSQI),GAD-7 (焦虑症) 和PHQ-9 (抑郁症) 问卷收集的数据.
- 统计分析包括单变量和多变量线性回归来确定显著的相关性.
主要成果:
- 全球平均PSQI得分为3.09,11.7%的患者睡眠质量差.
- 在PSQI得分和GAD-7 (r=0.158,P=0.005) 和PHQ-9 (r=0.246,P<0.001) 得分之间观察到显著的相关性.
- 较高的PHQ-9分数 (抑郁症) 和伴随性疾病的存在独立地与IBD患者的睡眠质量差相关.
结论:
- 在IBD患者中,睡眠障碍与抑郁症和并发症比与疾病本身的活动更密切相关.
- 对于有睡眠问题的IBD患者,建议对精神健康状况和并发症进行例行查.
- 需要进一步的研究来开发针对性干预措施,以改善这一患者群体的睡眠质量.
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