患有COVID-19的喘患者的血栓变化和血液学并发症:系统性审查
Gabriela Mara1,2, Gheorghe Nini2, Stefan Marian Frent3
1Multidisciplinary Doctoral School, Vasile Goldis Western University of Arad, 310414 Arad, Romania.
Diseases (Basel, Switzerland)
|October 28, 2025
概括
患有COVID-19 (冠状病毒疾病2019) 的喘患者没有显示出血栓或血液学问题的绝对增加风险. 需要更多的研究来了解喘是否会影响COVID-19.
科学领域:
- 肺部病理学 肺部病理学
- 血液学 血液学 血液学
- 传染性疾病 传染性疾病
背景情况:
- 喘和COVID-19 (冠状病毒疾病2019) 的相互作用引发了人们对血液学并发症的担忧.
- COVID-19与凝血病有关,但喘在这些风险中的独立作用尚不清楚.
研究的目的:
- 系统地审查SARS-CoV-2感染的喘患者血液学异常的证据.
- 为了调查D-二次体升高,血小板缺血和静脉血栓塞栓症 (VTE) 的风险.
主要方法:
- 在PubMed和Web of Science的系统文献搜索 (2020年1月至2025年5月).
- 包括报告喘COVID-19患者血液学结果的研究.
- 40项研究的定性综合包括由于异质性的研究.
主要成果:
- 在喘COVID-19患者中观察到的可变D-二元升高和血栓事件.
- 一些研究表明,急症监护室的入院率和血栓栓塞的风险更高,特别是在控制不良或非过敏的喘中.
- 结果不一致,受研究设计和缺乏喘分层的限制.
结论:
- 目前的证据不证实COVID-19中喘相关的血栓风险增加.
- 需要进一步的前性,分层研究,标准化终点.
- 需要澄清喘是否会改变SARS-CoV-2感染的血液过程.
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