约旦药剂师之间的药物相互作用管理:全国比较调查
Derar H Abdel-Qader1, Khalid Awad Al-Kubaisi2, Esra' Taybeh3
1Faculty of Pharmacy & Medical Sciences, University of Petra, Amman 11196, Jordan.
Pharmacy (Basel, Switzerland)
|October 28, 2025
概括
与社区药剂师相比,约旦的医院药剂师拥有更好的药物相互作用 (DDI) 知识. 解决实践设置差异需要量身定制的策略,包括社区环境的综合患者数据访问和改善医院的专业间动态,以提高药物安全.
科学领域:
- 药房实践 在药房实践.
- 药物安全 药物安全
- 卫生政策 卫生政策
背景情况:
- 药物相互作用 (DDI) 是可预防的患者伤害的重要原因.
- 多药和药物错误是约旦日益严重的挑战.
- 没有先前的研究系统地比较了约旦医院和社区药剂师的DDI管理.
研究的目的:
- 在约旦进行首次医院和社区药剂师之间对DDI管理的全国比较评估.
- 识别与DDI管理相关的知识,态度,做法和障碍的差异.
- 确定高DDI知识和最佳实践的预测因素.
主要方法:
- 一项涉及380名持牌药剂师 (175家医院,205家社区) 的全国性,横截面研究.
- 有比例的分层随机抽样和经过验证的在线问卷.
- 多变量物流回归分析以确定知识和实践的预测因素.
主要成果:
- 医院药剂师的客观DDI知识得分显著更高 (10.3比8.1,p<0.001).
- 主要障碍:社区药剂师缺乏患者数据访问;医院药剂师的工作量高和医生抵抗.
- 最佳实践与更高的知识 (AOR=1.25) 和医院环境 (AOR=3.65) 有关,但受到医生抵抗 (AOR=0.45) 的阻碍.
结论:
- 约旦医院和社区药剂师之间存在明显的知识和实践差距.
- 需要一项双重的国家战略:专注于医院的跨专业动态和社区药房的综合患者数据访问.
- 研究结果为解决实践设置差异和改善全球药物安全提供了一个模型.
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