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基因型组合和遗传风险评分分析MTHFR,MTRR和MTR多态性在甲状腺功能低下的敏感性:一个病例对照研究

Nilgun Tan Tabakoglu1, Arzu Ay2, Nevra Alkanli3

  • 1Health Practice and Research Center, Faculty of Medicine Hospital, Trakya University, Edirne 22100, Turkey.

Current issues in molecular biology
|October 28, 2025
PubMed
概括

MTRR和MTR基因的遗传变异与甲状腺功能低下风险有关. 特定的MTRR A66G和MTR A2756G基因型,单独或组合,显著增加疾病易感性和相关的代谢条件.

关键词:
叶酸的新陈代谢 叶酸的新陈代谢遗传风险因素 遗传风险因素遗传风险评分 遗传风险评分基因型组合分析 基因型组合分析同型半氨酸同型半氨酸甲状腺功能低下症 甲状腺功能低下症

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