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加强英格兰的MMR疫苗接种监测:比较和对比新的个人级别和现有的综合数据来源

Adam Pullen¹, Adewole Adekola¹, Katie Farnes¹

¹Immunisation and Vaccine-Preventable Diseases Division, UK Health Security Agency, 61 Colindale Avenue, London NW9 5EQ, United Kingdom.

International journal of medical informatics

|October 28, 2025

概括

来自免疫信息系统 (IIS) 的MMR疫苗接种数据现在与英国卫生安全局 (UKHSA) 监测的COVER和ImmForm等既有来源相一致. 这提高了MMR疫苗报告的准确性,并减少了不平等.

科学领域:

公共卫生公共卫生
疫苗接种监督工作
医疗信息学医疗信息学

背景情况:

英国卫生安全局 (UKHSA) 使用多个数据源 (COVER,ImmForm,IIS) 来监测英格兰的疫苗接种情况.
这些来源的公开可用的MMR疫苗接种统计数据缺乏经过验证的一致性,风险是报告不一致性.
不一致性可能会对疫情分析,干预和减少疫苗接种不平等的努力产生负面影响.

研究的目的:

为了量化MMR疫苗接种数据来源之间的统计一致性:COVER,ImmForm和免疫信息系统 (IIS).
为适当使用每个数据源提供上下文.
在IIS中验证新获取的MMR数据.

主要方法:

24个月和60个月的个人的MMR疫苗接种记录和覆盖率的比较.
按剂量分层,NHS调试地区和财年季度 (2022年4月 - 2023年6月).
对IIS和ImmForm数据与COVER数据源进行比较分析.

主要成果:

与COVER相比,ImmForm在接种疫苗的覆盖率上显示出极小的差异 (≤1.10%).
与COVER.相比,IIS在接种疫苗的覆盖率上表现出很大的差异 (≤6.90%).
IIS记录的疫苗记录明显少于COVER (n = -140,027),部分原因是缺少的记录被编码为药物系统化命名法产品代码.

结论:

免疫信息系统 (IIS) 负责缺失的记录,现在是MMR疫苗接种统计数据的一致来源,与COVER和ImmForm一起.
用户应评估数据源范围和其特定应用的差异.
保持多个数据源可以提高UKHSA的监控灵活性,并使交叉验证成为可能.

关键词:

儿童健康信息系统 (CHIS) 是一个儿童健康信息系统.数据处理服务 (DPS)电子健康记录 (EHR) 是一种电子医疗记录.麻疹,疹,红疹 (MMR) 是一个疾病.可识别个人信息 (PII)疫苗注册表 (注册) 是一个注册表.

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