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凝胺的脂化促进了其细胞吸收和抗瘤活性

Zhiwei Wang1, Xingjun Xu1, Hui Wen2

  • 1State Key Lab of Phytochemistry and Natural Medicines, Dalian Institute of Chemical Physics, CAS, Dalian 116023, China; Jiangxi Provincial Key Laboratory for Pharmacodynamic Material Basis of Traditional Chinese Medicine, Ganjiang Chinese Medicine Innovation Center, Nanchang 330000, China.

Bioorganic chemistry
|October 28, 2025
PubMed
概括

脂化凝衍生物对癌细胞具有增强的抗增殖活性. 中链脂质修饰,特别是GB5,提高了疗效和选择性,为癌症治疗研究提供了有前途的途径.

关键词:
凝胺是一种凝胺.脂质化 脂质化 是一种这就是ROSOS ROS.它具有抗瘤活性.灭症 (apoptosis) 是一种死亡的过程.细胞吸收细胞吸收.铁性化 (ferroptosis) 是一种

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