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Updated: Jan 13, 2026

In Vitro Drug Screening Against All Life Cycle Stages of Trypanosoma cruzi Using Parasites Expressing β-galactosidase
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In Vitro Drug Screening Against All Life Cycle Stages of Trypanosoma cruzi Using Parasites Expressing β-galactosidase

Published on: November 5, 2021

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持续修改Minimolide:结构和化模式对抗Trypanosoma cruzi活性的影响

Orlando G Elso1,2, Augusto E Bivona3,4, Valeria P Sülsen2,5

  • 1Laboratorio de Biocatálisis., Departamento de Química Orgánica y UMYMFOR, Naturales Universidad de Buenos Aires-CONICET, Facultad de Ciencias Exactas, Ciudad Universitaria, Pabellón 2 piso 3, C1428EGA, Buenos Aires, Argentina.

ChemMedChem
|October 28, 2025
PubMed
概括

使用脂酶进行生物催化,将天然化合物minimolide转化为更有效的抗Trypanosoma cruzi剂. 乙衍生物显示出增强的抗寄生虫活性和对寄生虫的选择性.

关键词:
试osoma cruzi 是一种类型的虫.查加斯病 查加斯病脂酶脂酶的使用方法最少的一种是最小化物.

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