[扩展配置的"鼓形"气球可扩展支架的结构设计和机械分析]
Youzhi Zhao1,2, Qianwen Hou3, Jianye Zhou3
1Department of Biomedical Engineering, College of Chemistry and Life Sciences, Beijing University of Technology, Beijing 100124, P. R. China.
概括
一种新的"鼓形"主动脉支架被设计用于防止跨导管植入后的迁移. 机械分析证实了其良好的抗迁移性能和耐疲劳性.
科学领域:
- 生物医学工程 生物医学工程
- 心血管器械 心血管器械
- 机械分析 机械分析
背景情况:
- 支架迁移是跨导管植入的常见并发症.
- 现有的支架设计可能无法充分防止迁移,对患者构成风险.
研究的目的:
- 设计和机械分析一个"鼓形"气球可扩展的大动脉支架.
- 为了评估支架的抗迁移性能和耐疲劳性.
主要方法:
- 使用数值模拟和体外实验来评估植入过程.
- 使用脉动式循环负荷和古德曼图来评估疲劳性能.
- 通过模拟支架迁移和分析力位移曲线来评估反迁移性能.
主要成果:
- 所有五种支架模型都缩成14F外,并均扩展本地门的说明书.
- 支架应力仍然低于最终应力,表明没有疲劳骨折.
- 车型S5展示了最小的接触面积,但最高的平均接触力 (0.16MPa) 和最大的抗迁移力 (10.73N).
结论:
- 设计的"鼓形"支架有效地扩展并展现出有前途的反移民能力.
- 支架设计显示出良好的疲劳性能,对于长期植入至关重要.
- 优化支架几何形状,就像细胞高度比率一样,影响接触力学和抗迁移力.
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