一个昼夜的早晨复合体调节了Arabidopsis的远红色光信号
Chen Su1,2, Yumei Qin1,2, Yingjun Yu1,2
1State Key laboratory of Forage Breeding-by-Design and Utilization and Key laboratory of Plant Molecular Physiology, Institute of Botany, Chinese Academy of Sciences, Beijing, China.
Nature communications
|October 29, 2025
概括
植物的昼夜时钟使用早晨综合体 (MC) 调节黎明时光信号和基因表达. 这个综合体,包括咖啡时间 (TIC),环形时钟协会1 (CCA1) 和晚延长的海马座 (LHY),确保植物适应光线线.
科学领域:
- 植物生物学 植物生物学
- 分子生物学分子生物学
- 时间生物学 时间生物学
背景情况:
- 植物的昼夜时钟同步生理过程与环境周期,特别是光线.
- 生物钟调节光信号的反机制尚未得到充分理解.
研究的目的:
- 研究咖啡时间 (TIC) 蛋白质的作用及其与核心时钟组件的相互作用在调节光信号通路中的作用.
- 阐明昼夜时钟反如何调节分子层面的光反应,特别是在黎明时.
主要方法:
- 确定TIC,CIRCADIAN CLOCK ASSOCIATED1 (CCA1) 和LATE ELONGATED HYPOCOTYL (LHY) 之间的蛋白质相互作用.
- 对基因表达模式的分析,专注于参与光信号和昼夜调节的基因.
- 在不同的光条件下对突变植物 (例如,tic, cca1, lhy突变植物) 的表型分析,包括远红光.
主要成果:
- 在核中,TIC,CCA1和LHY形成了一个"早晨综合体" (MC),在黎明时刻共同抑制许多基因.
- 该MC直接结合到PHYTOCHROME A (PHYA) 和其他PhyA信号组件的促进者,在黎明时抑制它们的表达.
- 缺少CCA1和LHY的突变体对远红光的敏感性增加,反映了突变体的表型,表明它们具有合作作用.
结论:
- 昼夜MC作为一个关键的复合体,提供光信号的反调节.
- 这种复合体调解着各种黎明特定的生物过程,包括调节对光的反应中阴囊细胞生长.
- 这些调节功能对于优化植物适应日常环境变化的能力至关重要.
相关概念视频
02:45Biological Clocks and Seasonal Responses
41.5K
The circadian—or biological—clock is an intrinsic, timekeeping, molecular mechanism that allows plants to coordinate physiological activities over 24-hour cycles called circadian rhythms. Photoperiodism is a collective term for the biological responses of plants to variations in the relative lengths of dark and light periods. The period of light-exposure is called the photoperiod.
41.5K
02:00Photoreceptors and Plant Responses to Light
28.3K
Light plays a significant role in regulating the growth and development of plants. In addition to providing energy for photosynthesis, light provides other important cues to regulate a range of developmental and physiological responses in plants.
28.3K
02:19Circadian Rhythms and Gene Regulation
4.5K
The biological clock is involved in many aspects of regulating complex physiology in all animals. It was in 1935 when German zoologists, Hans Kalmus and Erwin Bünning, discovered the existence of circadian rhythm in Drosophila melanogaster. However, the internal molecular mechanisms behind the circadian clock remained a mystery until 1984, when Jeffrey C. Hall, Michael Rosbash, and Michael W. Young discovered the expression of the Per gene oscillating over a 24-hour cycle. In subsequent...
4.5K
01:25Cell Signaling in Plants
6.1K
Plant cells communicate to coordinate their cycle of growth, flowering and fruiting, and activities in roots, shoots, and leaves in response to the changing environmental conditions. Plant signaling is distinct from animal signaling. Plants primarily utilize enzyme-linked receptors, whereas the largest class of cell-surface receptors in animals are G-protein coupled receptors (GPCRs). Unlike animals, receptor tyrosine kinases are rare in plants. Instead, plants have a diverse class of...
6.1K
01:15The Antenna Complex
7.6K
Plants and other photosynthetic organisms comprise pigments capable of absorption of direct sunlight. These pigments are present in the reaction center - the main site of photochemical reactions as well as in the antenna complex. Under average light conditions, the rate at which reaction center pigments absorb light is far below the electron transport chain's capacity. As a result, the reaction center alone cannot provide enough energy to drive photosynthesis. The photosynthetic efficiency can...
7.6K
01:11Channel Rhodopsins
3.1K
Most organisms use photoreceptors to sense and respond to light. Examples of photoreceptors include bacteriorhodopsins and bacteriophytochromes in some bacteria, phytochromes in plants, and rhodopsins in the photoreceptor cells of the vertebral retina. The light-sensitive property of these receptors is because of the bound chromophores, such as bilin in the phytochromes and retinal in the rhodopsins.
Rhodopsins belong to the family of cell surface proteins called G-protein coupled receptors,...
Rhodopsins belong to the family of cell surface proteins called G-protein coupled receptors,...
3.1K