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Updated: Jan 13, 2026

Characterize Disease-related Mutants of RAF Family Kinases by Using a Set of Practical and Feasible Methods
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在非小细胞肺癌中BRAF突变的多样性以及对治疗的影响

Kevin Lu1, John Paul Shen2, Fernando J Lopez-Diaz3

  • 1UC San Diego, La Jolla, CA, USA.

NPJ precision oncology
|October 29, 2025
PubMed
概括

在非小细胞肺癌 (NSCLC) 中,BRAF-MEK 抑制剂提高了具有I类BRAF突变的存活率. 非典型的BRAF变体表现出不同的依赖性,需要为NSCLC患者量身定制的治疗策略.

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