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Updated: Jan 13, 2026

Optimized LC-MS/MS Method for the High-throughput Analysis of Clinical Samples of Ivacaftor, Its Major Metabolites, and Lumacaftor in Biological Fluids of Cystic Fibrosis Patients
06:14

Optimized LC-MS/MS Method for the High-throughput Analysis of Clinical Samples of Ivacaftor, Its Major Metabolites, and Lumacaftor in Biological Fluids of Cystic Fibrosis Patients

Published on: October 15, 2017

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基于FAERS数据库的维多利祖马布不良事件的药监测研究

Guanghui Yuan1, Jie Liu2, Yi Xu3

  • 1Affiliated Hospital of Nanjing University of Chinese Medicine, Jiangsu Province Hospital of Chinese Medicine, No.155, Hanzhong Road, Qinhuai District, Nanjing, Jiangsu Province, China.

Scientific reports
|October 29, 2025
PubMed
概括

这项研究分析了FDA不良事件报告系统对vedolizumab (Entyvio®) 的数据,确定了严重的安全风险,如胃肠道疾病和感染. 这些发现支持了关于vedolizumab使用的知情临床决策.

关键词:
不良事件是不良事件.公平的人是公平的.药物监督 药物监督 药物监督这就是Vedolizumab.

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Dynamic Adhesion Assay for the Functional Analysis of Anti-adhesion Therapies in Inflammatory Bowel Disease08:27

Dynamic Adhesion Assay for the Functional Analysis of Anti-adhesion Therapies in Inflammatory Bowel Disease

Published on: September 20, 2018

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Body:In certain scenarios, in vitro dissolution tests can replace in vivo bioequivalence studies. This is particularly true when a drug product, though available in varying strengths, maintains proportional similarity in its active and inactive ingredients. In such cases, the need for in vivo bioequivalence studies for lower strength variants may be waived, provided dissolution tests and in vivo studies on the highest strength yield satisfactory results.Bioequivalence can be indicated through...
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