在脑成像中,对多b值MUSE-DWI和SS-EPI-DWI之间的图像质量,ADC和IVIM数据的比较研究
Wei Wang1, Weinan Xu1, Shengjie Hu1
1Department of Radiology, Integrated Traditional Chinese and Western Medicine Hospital of Wenzhou Medical University, No. 75, Jinxiu Road, Lucheng District, Wenzhou, Zhejiang, 325000, China.
BMC medical imaging
|October 29, 2025
概括
复杂感度编码扩散成像 (MUSE-DWI) 在脑成像中提供了优越的图像质量,相比单射回声平面成像扩散加权成像 (SS-EPI-DWI). 然而,表面扩散系数 (ADC) 和内不连贯运动 (IVIM) 参数需要在较低的b值时用MUSE-DWI仔细解释.
科学领域:
- 放射学和医学成像学 医学成像学
- 神经成像技术的神经成像技术
- 扩散式核磁共振成像 (MRI)
背景情况:
- 扩散加权成像 (DWI) 对于大脑成像至关重要.
- 多重感应编码扩散成像 (MUSE-DWI) 旨在提高图像质量,而不是单次回声平面成像扩散加权成像 (SS-EPI-DWI).
- 了解对明显扩散系数 (ADC) 和内不连贯运动 (IVIM) 等定量参数的影响至关重要.
研究的目的:
- 为了比较双边基底质中的MUSE-DWI和SS-EPI-DWI之间的图像质量,ADC和IVIM参数.
- 为了评估文物减少和信号与噪声比 (SNR) 的差异.
- 评估两种技术的ADC值和b值之间的关系.
主要方法:
- 对34名患者脑部扫描的回顾性分析.
- 技术人员对艺术品的独立评估和ADC地图匹配.
- 对SNR,ADC,真正的扩散系数 (D),伪扩散系数 (D*) 和 perfusion 分数 (f) 的定量分析.
- 统计分析包括相关性和一致性评估 (斯皮尔曼的rho,弗莱斯的卡帕,ICC).
主要成果:
- 与SS-EPI-DWI相比,MUSE-DWI显示出明显更好的文物减少,融合地图匹配和SNR (P <0.05).
- 在MUSE-DWI和SS-EPI-DWI之间观察到ADC,D,D*和f的显著差异,b值为20-600s/mm2 (P <0.05).
- 在两组中,ADC值随着b值的增加而下降,具有强烈的负相关性 (斯皮尔曼的 ρ ≈ -0.85 到 -0.90,P < 0.01).
结论:
- 在3.0T的MRI中,MUSE-DWI提供了更高质量的基底腺节图像,扭曲率降低.
- 在b值<1000s/mm2时,MUSE-DWI的ADC值始终低于SS-EPI-DWI,在较低的b值时差异变大.
- 在对不同b值的MUSE-DWI的ADC和IVIM数据进行解释时,建议谨慎使用;需要进一步的研究.
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