怀孕和预怀孕队伍的景观:一个范围审查
Lauren Maxwell1, Regina Gilyan2, Sayali Arvind Chavan3
1Heidelberg Institute of Global Health, Universitätsklinikum Heidelberg, Im Neuenheimer Feld 130/3, Heidelberg, Germany. lauren.maxwell.us@gmail.com.
BMC pregnancy and childbirth
|October 29, 2025
概括
这次对妊娠队列的审查揭示了研究母亲暴露的差距,如传染病和环境因素,以及儿童的结果,如微生物组和免疫功能. 未来的研究应该针对这些代表性不足的领域,以获得更好的发展见解.
科学领域:
- 生命过程流行病学的流行病学.
- 发展成果的发展结果.
- 孕产妇和儿童的健康
背景情况:
- 怀孕和怀孕前的暴露显著影响了以后的人生发展结果.
- 现有的怀孕和预怀孕队伍对于理解这些影响至关重要.
- 需要全面的概述来识别研究缺口.
研究的目的:
- 识别和描述已完成或正在进行的怀孕和孕前群体.
- 评估这些队列中测量母亲暴露和儿童结果的差距.
- 为未来对母婴健康研究的研究投资提供信息.
主要方法:
- 在四个生物医学数据库中使用文本和MeSH术语进行系统的文献搜索.
- 阿斯基和奥马利范围审查方法的应用.
- 由两名审核员进行独立选和数据绘制,第三名审核员解决差异.
主要成果:
- 审查了147个手稿,涵盖56个怀孕和2个怀孕前的队列 (23个正在进行).
- 通常测量母亲的暴露:营养,人体测量,非传染性疾病 (NCD),人口统计. 常见的儿童结果:精神,行为,神经发育,身体.
- 代表性不足的暴露:传染病,生物标志物,环境/工作场所,疫苗,气候. 代表性不足的结果:微生物组,免疫功能,经济.
结论:
- 该审查为妊娠和妊娠前研究的跨队列协调提供了基础.
- 在评估传染病,疫苗,环境和气候相关暴露方面存在重大差距.
- 进一步的研究应侧重于代表性不足的母体暴露和儿童结果,如微生物组和免疫功能.
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