TSPO有助于阿尔茨海默氏病的神经病理学和认知缺陷

Kelly Ceyzériat1, Aurélien M Badina2, Laurene Abjean2,3

  • 1CIBM Center for Biomedical Imaging, Geneva, Switzerland.

PubMed
概括

18kDa转位蛋白 (TSPO) 与阿尔茨海默病 (AD) 的进展有关. 在小鼠模型中降低TSPO改善了葡萄糖吸收,降低了有毒蛋白质聚合物,并保留了记忆力,这表明TSPO是治疗目标.

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