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Updated: Jan 13, 2026

Identification of Kinase-substrate Pairs Using High Throughput Screening
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在蛋白质激酶中区分激活,失活和抵抗变体

Gurdeep Singh1, Torsten Schmenger1, Juan Carlos Gonzalez-Sanchez1

  • 1BioQuant & Biochemistry Center, Heidelberg University, Im Neuenheimer Feld 267, Heidelberg, 69121, Germany.

Genome medicine
|October 29, 2025
PubMed
概括

识别增加蛋白质功能的激酶变体是个性化医学的关键. 我们的新计算方法准确地预测了激活,关闭和抗性变体,帮助临床决策.

关键词:
癌症基因组学 癌症基因组学功能获取 - 功能获取遗传变体的遗传变体功能丧失 - 功能丧失.机器学习是机器学习.精准医学是一门精准的医学.蛋白质激酶酶是一种蛋白质激酶.电阻 电阻 电阻 电阻 电阻 电阻变异性病原性预测的变异性.

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