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相关概念视频

Brain Imaging01:14

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Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
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The brain is the most complex organ in the human body. It consists of four main parts: the cerebrum, diencephalon, cerebellum, and brainstem.
The cerebrum is the largest section of the brain and divides into left and right hemispheres, separated by a deep fissure. The cerebral outer layer of grey matter — the cerebral cortex — comprises elevations called gyri and shallow groves called sulci. The inner portion of white matter includes long nerve fibers known as axons, which connect...
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Introduction:Magnetic Resonance Imaging, or MRI, can include a specialized imaging technique of the urinary system known as Magnetic Resonance Urography (MRU). This radiation-free technique uses strong magnetic fields and radio waves to produce detailed images with the help of a computer. MRU is particularly effective for visualizing fluid-filled structures like the kidneys, ureters, and bladder.Applications of MRI in the Genitourinary SystemKidneys and Ureters: MRI detects tumors, cysts,...
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Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...
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Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
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相关实验视频

Updated: Jan 13, 2026

Whole-brain Segmentation and Change-point Analysis of Anatomical Brain MRI&#8212;Application in Premanifest Huntington's Disease
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区域大脑体积在成年期的变化:使用MRI数据的多队列研究.

Jae Hyuk Shim1, Hyeon-Man Baek1,2, Jung Hoon3

  • 1MTech Lab Co., Ltd., Room B1027, 119, Songdo Munhwa-ro, Yeonsu-gu, Incheon 21985, Republic of Korea.

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概括

随着年龄的增长,大脑结构发生变化,心室显著膨胀,前额叶和头顶叶收缩. 这为正常衰老与疾病提供了一个参考.

关键词:
这就是为什么MRI是MRI.大脑衰老 老龄化神经退行症的神经退行症神经成像是一种神经成像.结构变化 结构变化卷积分析 卷积分析

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科学领域:

  • 神经成像是一种神经成像.
  • 大脑衰老 老化大脑
  • 认知神经科学 认知神经科学

背景情况:

  • 与年龄相关的大脑结构变化对于理解认知衰老和神经退行性疾病至关重要.
  • 在成年期表征规范性大脑体积变化对于识别健康衰老的偏差至关重要.

研究的目的:

  • 在成年期 (年龄21-90岁) 的95个大脑区域中全面绘制与年龄相关的体积变化.
  • 整合多种MRI数据集 (韩国,IXI,ADNI) 以进行规范性大脑衰老的强有力的表征.

主要方法:

  • 利用一个优化的神经成像管道与先进的预处理和神经网络细分在T1加权的MRI从1833个认知健康的个人.
  • 分析了七个年龄段的体积数据,与FreeSurfer相比验证了管道可靠性 (平均ICC:0.9965).
  • 对性别和队列效应进行了校正,然后计算了整个生命周期内双边大脑体积的百分比变化.

主要成果:

  • 观察到白质过敏度 (122.6%) 和侧腔室 (115.9%) 的显著体积膨胀.
  • 在额头 (三角形: 21.5%),头部 (下面的头部: 20.4%),部 (横向的部: 21.6%) 和带状皮层 (16.1%) 中记录了中度到显著的收缩.
  • 在insula (3.7%) 和pallidum (2.6%) 中发现了最小的体积变化.

结论:

  • 这项研究为整个成年期的规范性区域大脑体积变化提供了全面的参考.
  • 突出了与年龄相关的大脑体积变化的实质性区域间变异性.
  • 提供了区分正常衰老和大脑早期病理变化的基础.