饮食草改善了糖尿病前期成人血清抗氧化剂概况:一个为期28周的随机对照交叉试验
Shauna Groven1,2, Pamela Devillez1, Robert Hal Scofield3
1Department of Kinesiology and Nutrition Sciences, University of Nevada, Las Vegas, NV 89154, USA.
Antioxidants (Basel, Switzerland)
|October 29, 2025
概括
每天冷干燥的草 (FDS) 改善了抗氧化剂状态,并降低了糖尿病前期的成年人禁食葡萄糖. 这种饮食干预也对血管炎症的标志物产生了积极的影响,支持FDS作为糖尿病前期管理的有益补充.
科学领域:
- 营养科学 营养科学
- 代谢健康 代谢健康
- 预防心血管疾病 预防心血管疾病
背景情况:
- 前糖尿病会增加氧化压力,增加2型糖尿病和心血管疾病的风险.
- 虽然富含抗氧化剂的草显得有前途,但它们对特定抗氧化剂标记物的影响尚不清楚.
- 现有研究强调了针对糖尿病前期氧化应激和炎症的干预措施的必要性.
研究的目的:
- 评估冷干燥草 (FDS) 对糖尿病前期成年人的禁食葡萄糖,血清抗氧化剂状况和血管炎症的影响.
- 评估FDS作为一种潜在的饮食干预措施,用于管理糖尿病前期并发症.
- 确定FDS对与氧化应激和炎症相关的关键生物标志物的影响.
主要方法:
- 一项为期28周的随机对照交叉试验,涉及糖尿病前期的成年人,而不是服用降血糖药物.
- 参与者每天摄入32g的FDS或对照 (常规饮食) 每人12周,每次4周的洗期.
- 包括禁食葡萄糖,抗氧化酶,抗氧化能力,胡卜素和粘附分子在内的生物标志物在多个时间点被测量.
主要成果:
- FDS显著改善了血清超氧化物脱酶,谷氨 (GSH),抗氧化能力 (AC) 和β-胡卜素水平.
- 摄入FDS导致禁食葡萄糖水平显著降低.
- 血管炎症的标记物,细胞间粘附分子 (ICAM) 和血管细胞粘附分子 (VCAM),随着FDS消费而显著减少.
- ICAM和VCAM显示与GSH,AC和β-胡卜素的反相关性,表明一种抗氧化剂介导的效果.
结论:
- 草的消费,特别是冷干燥的草,可以成为改善糖尿病前期成人血糖控制的宝贵饮食策略.
- 摄入FDS可以增强抗氧化剂的状态,并对血管炎症的标志物产生积极影响.
- 这些发现支持将草纳入糖尿病前期管理的饮食建议,以减轻相关的健康风险.
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