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Updated: Jan 13, 2026

Enhanced Genome Editing with Cas9 Ribonucleoprotein in Diverse Cells and Organisms
09:51

Enhanced Genome Editing with Cas9 Ribonucleoprotein in Diverse Cells and Organisms

Published on: May 25, 2018

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来自Cohnella algarum的美索菲尔亚格诺亚特介导可编程DNA/RNA裂变,具有独特的指导特异性

Yanhong Peng1, Wang Pan1, Yang Wang1

  • 1State Key Laboratory of Biocatalysis and Enzyme Engineering, Hubei Key Laboratory of Industrial Biotechnology, School of Life Sciences, Hubei University, Wuhan 430062, China.

Biomolecules
|October 29, 2025
PubMed
概括

这项研究描述了来自Cohnella algarum的 prokaryotic Argonaute (pAgo) CalAgo,揭示了其在生理温度下的DNA和RNA内核酶活动. 卡尔阿戈表现出独特的指导长度特异性和对不匹配的敏感性,这表明核酸应用的潜力.

关键词:
针对DNA和RNA的向.具有独特的指南特异性.中性恋的阿尔戈诺特人

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