营养查工具可以预测患有败血症的重症患者的预后吗?
Duygu Kayar Calili1, Demet Bolukbasi2, Seval Izdes1
1Department of Anesthesiology and Reanimation-Intensive Care, Faculty of Medicine, Yıldırım Beyazıt University Ankara Bilkent City Hospital, Ankara 06800, Turkey.
Medicina (Kaunas, Lithuania)
|October 29, 2025
概括
营养查工具 (NST) 可以预测败血症患者的结果. 在重症患者中高的5日营养风险 (NUTRIC) 评分独立预测了重症监护病房患者的死亡率.
科学领域:
- 关键护理医学 关键护理医学
- 营养科学 营养科学
- 预测生物标志物 预测生物标志物
背景情况:
- 营养状况显著影响了败血症患者的临床结果.
- 关于营养查工具 (NST) 在这个人群中的预后价值的研究有限.
- 早期和持续的营养评估对于管理重症患者至关重要.
研究的目的:
- 评估重症监护室 (ICU) 中五种NST的预后能力.
- 为了比较NST在ICU入院和第5天的预测值.
- 确定与败血症死亡率相关的特定NST.
主要方法:
- 对成年败血症ICU患者进行前性观察性研究.
- 包括126名患者,分为幸存者 (n=97) 和非幸存者 (n=29).
- 在入院和第五天评估五个NST (CONUT,PNI,NRS-2002,GNRI,NUTRIC),并进行多变量和ROC分析.
主要成果:
- 与幸存者相比,非幸存者表现出较高的CONUT和NUTRIC得分和较低的PNI得分.
- 多变量分析显示,较高的第5天NUTRIC评分独立与死亡率增加有关.
- 接收器操作特征 (ROC) 分析表明,NUTRIC评分> 6作为死亡率的预测指标.
结论:
- 虽然幸存者和非幸存者群体之间有几个营养标志物有所不同,但5日NUTRIC得分成为评估NSTs中唯一独立的死亡率预测指标.
- 这些发现突显了NUTRIC得分在重症败血症患者的预后意义.
- 使用NUTRIC评分对营养风险的第5天评估可能有助于识别针对性干预的高风险患者.
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