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Updated: Jan 13, 2026

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针对癌症治疗的Ras 1 (KSR1) 的向激酶抑制剂

Hyuk Moon1, Hyunjung Park1, Soyun Lee1

  • 1Department of Genetics and Biotechnology, College of Life Sciences, Kyung Hee University, Yongin-si 17104, Gyeonggi-do, Republic of Korea.

Pharmaceutics
|October 29, 2025
PubMed
概括

RAS/MAPK通路驱动癌症,虽然BRAF/MEK抑制剂起作用,但耐药性很常见. 拉斯1的激酶抑制剂 (KSR1) 是一个关键的调节剂,向它显示了癌症治疗的希望,特别是肝细胞癌.

关键词:
在 RAS/MAPK 信号中.肝细胞癌是肝细胞癌.Ras 1 的激酶抑制剂 1 的激酶抑制剂脚手架中的蛋白质.有针对性的治疗.

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