加速式CXL与加速式隐形眼镜辅助CXL治疗进展性角质-一个3年的追溯比较随访
Anna Bunin1,2, Shmuel Kagasov1, Nir Amitai2,3
1Department of Ophthalmology, Soroka University Medical Center and Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva 84101, Israel.
Journal of clinical medicine
|October 29, 2025
概括
加快的隐形眼镜辅助角膜交叉链接 (A-CACXL) 提供了有效的,长期治疗角膜薄在角膜病患者. 结局结果与在角膜较厚的患者中标准的加速角膜交叉链接 (A-CXL) 相似.
科学领域:
- 眼科医生 眼科 眼科
- 角膜外科手术 角膜外科手术
- 视觉科学 视觉科学 视觉科学
背景情况:
- 角膜的管理通常需要角膜交叉连接.
- 薄角膜 (<400微米) 对标准A-CXL提出了挑战.
- 隐形眼镜辅助角膜交叉链接 (A-CACXL) 是薄角膜的替代方案.
研究的目的:
- 比较A-CXL和A-CACXL的长期临床和断层扫描结果.
- 评估A-CACXL在患有角膜薄的患者中的疗效.
- 评估A-CACXL.之后的角质进展情况.
主要方法:
- 回顾性队列研究 (2015-2018) 比较A-CXL (n=32) 和A-CACXL (n=30).
- 患者的角膜最小厚度≥400微米 (A-CXL) 或<400微米 (A-CACXL).
- 临床和断层扫描数据的3年随访.
主要成果:
- 这两组在最佳校正视敏度方面均显著改善.
- 术后断层扫描参数 (Kmax,Kmean,纹) 在两组之间是相似的.
- 在87% (A-CXL) 和73% (A-CACXL) 的眼睛中,角质的进展停止了.
结论:
- A-CACXL是一种安全有效的治疗角膜薄的角质.
- 在适合患者中,A-CACXL的长期结果与A-CXL相似.
- A-CACXL扩大了挑战角病例的交叉链接选项.
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