骨关节炎与韩国人群中的甘油三糖指数之间的关联:一项大型跨部门研究
1Department of Computer Science and Engineering, Konkuk University, Seoul 05029, Republic of Korea.
Journal of clinical medicine
|October 29, 2025
概括
甘油三糖 (TyG) 指数与韩国人的骨关节炎 (OA) 没有联系. 综合的TyG和肥胖指标显示,与OA的关联比单个肥胖指标更弱.
科学领域:
- 代谢综合征研究 代谢综合征研究
- 骨关节炎流行病学 流行病学
- 生物标记分析 生物标记分析
背景情况:
- 骨关节炎 (OA) 是一种普遍的疾病,与甘油三糖指数 (TyG) 有着争论的关联.
- 研究TyG指数,肥胖和OA之间的关系对于了解疾病风险因素至关重要.
研究的目的:
- 为了检查TyG指数与韩国人口中OA的关联.
- 探索TyG指数和肥胖指标 (BMI,WC,WHtR) 对OA患病率的综合影响.
主要方法:
- 一项涉及15128名韩国成年人的大规模横截面研究.
- 复杂的样本二元物流回归分析被用来评估关联.
- 对于多次比较,应用了邦费罗尼校正,以确保统计的严谨性.
主要成果:
- 整体OA患病率为男性7.3%,女性24.3%.
- 仅仅TyG指数在调整后,在两种性别中都没有显著的关联与OA.
- 综合的TyG-肥胖指数 (TyG-BMI,TyG-WC,TyG-WHtR) 在女性中显示出强烈的关联与OA,但在男性中没有.
结论:
- 在韩国人群中,TyG指数与骨关节炎没有独立相关.
- 结合的TyG-肥胖指数显示,与个人肥胖指标 (如BMI,WC和WHtR) 相比,与OA的关联较弱.
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