在体外生命支持后与管相关的深静脉血栓症:前性诊断研究
Alexander Hermann1, Jannis Krais1, Anna-Maria Tremetsberger1
1Intensive Care Unit 13i2, Department of Medicine I, Medical University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, Austria.
Journal of clinical medicine
|October 29, 2025
概括
深静脉血栓症 (DVT) 影响35%的危急病患者在体外生命支持 (ECLS). 静脉结构是DVT的重要危险因素,强调了需要改进的血栓预防策略.
科学领域:
- 关键护理医学 关键护理医学
- 心血管医学 心血管医学
- 血管外科 血管外科
背景情况:
- 静脉血栓塞栓症 (VTE),包括深静脉血栓症 (DVT) 和肺栓塞 (PE),是需要体外生命支持 (ECLS) 的重症患者的重大并发症.
- 管相关的DVT在接受ECLS的患者中是一个特殊的关注点.
研究的目的:
- 在接受ECLS的成年ICU患者中确定管相关的DVT的患病率.
- 在这个患者群体中确定与DVT相关的风险因素.
主要方法:
- 未来的诊断研究在一个大学三级医院的两个ICU中进行.
- 包括101名在2016年至2021年期间接受ECLS的成年患者.
- 通过血管超声波或死后检查评估DVT;通过CT扫描或死后检查诊断PE.
主要成果:
- 总体上,DVT的患病率为35%,PE的患病率为9%.
- 患有DVT的患者患上PE的发病率明显较高 (23%对2%,p<0.001).
- 与静脉 (VA) ECLS相比,静脉 (VV) ECLS配置被确定为DVT的独立风险因素 (OR = 0.12,p = 0.0004).
结论:
- 在ECLS后的患者中存在大量的DVT患病率,VV配置是显著的风险因素.
- 由于PE的发病率很高,因此需要为ECLS患者进行例行查和量身定制的血栓预防方案.
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