在2021-2022年和2022-2023年季节在墨西哥儿童中传播RSV亚型A和B
Selene Zárate1, Blanca Taboada2, Karina Torres-Rivera1
1Posgrado en Ciencias Genómicas, Universidad Autónoma de la Ciudad de México, Ciudad de México 03100, Mexico.
Pathogens (Basel, Switzerland)
|October 29, 2025
概括
墨西哥儿童的呼吸道同胞体病毒 (RSV) 动态显示,在两个季节内从RSV-B转变为RSV-A. 基因组监测对于监测多样性和为公共卫生战略提供信息至关重要.
科学领域:
- 儿童传染病 儿童传染病
- 病毒学 病毒学
- 基因组流行病学 基因组流行病学
背景情况:
- 呼吸道共囊病毒 (RSV) 是全球和墨西哥儿童肺炎的主要原因.
- 了解RSV流行病学对于公共卫生干预至关重要.
研究的目的:
- 调查墨西哥肺炎的幼儿的RSV流行病学和遗传多样性.
- 分析两个连续季节的RSV趋势和共感染模式.
主要方法:
- 一项多中心研究分析了2021年8月至2023年7月肺炎的5岁以下儿童的呼吸道样本.
- 多重复合RT-PCR用于病原体识别.
- 进行了G和F蛋白的基因测序,用于谱系分析.
主要成果:
- 确诊了203例RSV病例,123例RSV-B和80例RSV-A. 这些病例包括:
- RSV-B在2021-2022年占主导地位,而RSV-A在2022-2023年占主导地位.
- 77%的样本具有共感染,最常见的是与鼻病毒,流感血球菌和肺炎菌.
- 与RSV-B (B.D.E.1) 相比,RSV-A显示出更大的血统多样性 (A.D.1,A.D.1.8,A.D.5.2).
- 基因组数据表明,从北美反复引入,局部循环持续有限.
结论:
- 墨西哥的RSV循环模式在2021-2022和2022-2023赛季之间发生了转变.
- 基因组监测对于跟踪RSV多样性,评估疫苗有效性和指导墨西哥公共卫生战略至关重要.
更多相关视频
09:01An In vitro Model to Study Immune Responses of Human Peripheral Blood Mononuclear Cells to Human Respiratory Syncytial Virus Infection
Published on: December 10, 2013
8.3K
09:14An Improved and High Throughput Respiratory Syncytial Virus RSV Micro-neutralization Assay
Published on: January 26, 2019
11.4K
相关概念视频
Rous Sarcoma Virus (RSV) and Cancer
6.2K
Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...
6.2K
Common Respiratory Disorders
1.3K
Respiratory disorders, a prevalent health concern globally, are generally divided into two primary categories: upper and lower respiratory tract disorders. The categorization is based on the area of the respiratory system they affect.
Upper respiratory disorders impact the airways above the vocal cords, encompassing areas like the nose, sinuses, and throat. Various conditions fall under this category, including the common cold and allergic rhinitis. These disorders can stem from several causes,...
Upper respiratory disorders impact the airways above the vocal cords, encompassing areas like the nose, sinuses, and throat. Various conditions fall under this category, including the common cold and allergic rhinitis. These disorders can stem from several causes,...
1.3K
Vaccinations
51.2K
Overview
51.2K
Respiratory Volumes
2.8K
Respiratory volumes are crucial metrics, meticulously measured to quantify the air exchanged in and out of the lungs during various phases of the breathing cycle. These precise measurements are vital for assessing lung function, diagnosing respiratory conditions, and monitoring overall respiratory health. Each parameter provides specific insights into the mechanics of breathing and the functional capacity of the lungs.
Tidal Volume (TV) Tidal volume (TV) is the air inhaled or exhaled in a...
Tidal Volume (TV) Tidal volume (TV) is the air inhaled or exhaled in a...
2.8K
Respiratory Volumes and Capacities
4.9K
The respiratory system is responsible for the intake of oxygen and the expulsion of carbon dioxide from the body. Respiratory volumes describe the volume of air in the lungs at different phases of the respiratory cycle. Tidal volume is the air breathed in and out during normal, quiet breathing. Inspiratory reserve volume is the air that can be forcefully inspired beyond the tidal volume. In contrast, expiratory reserve volume refers to the air that can be expelled from the lungs after a normal...
4.9K
