在紧急护理研究中的集群随机试验.
Howard S Kim1,2, Jacob M Schauer3, Jody D Ciolino3
1Department of Emergency Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
集群随机试验在紧急护理研究中很常见. 本综述为研究人员和临床医生解释了它们的特征,理由和局限性.
科学领域:
- 紧急护理研究方法的方法学.
- 临床试验的设计
背景情况:
- 集群随机试验 (CRT) 越来越多地被用于紧急护理.
- CRT涉及将组 (集群) 分配给干预,与个人随机化不同.
研究的目的:
- 审查CRT在紧急护理中的关键术语和特征.
- 描述CRT的合理性和局限性.
- 提供关于进行和评估CRT的指导.
主要方法:
- 对集群随机试验的方法审查.
- 讨论群组随机化而不是个人随机化的理由.
- 确定常见的局限性和评估考虑因素.
主要成果:
- 选择CRT是为了防止污染,为了方便物流,或为面向群体的干预.
- 弱点包括更大的样本大小,令人眼花乱的挑战和潜在的基线失衡.
- 评估需要评估CRT的理由,考虑类内相关性和参与者的同意.
结论:
- 在紧急护理中,CRT非常普遍,特别是在教育或EHR干预方面.
- 本综述为临床医生和研究人员提供了CRT的基础知识.
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