索波拉基尼尼斯 (Sophora tonkinensis) 增强了cGAS-STING通路的激活,并抑制了HBV复制的发生

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Updated: Jan 13, 2026

Dissecting Innate Immune Signaling in Viral Evasion of Cytokine Production
08:32

Dissecting Innate Immune Signaling in Viral Evasion of Cytokine Production

Published on: March 2, 2014

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Yuanyuan Guo1,2, Jincai Wen2,3, Xueting Wang4

  • 1School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, China.

Frontiers in pharmacology
|October 29, 2025
PubMed
概括

索波拉基尼尼斯 (Sophora tonkinensis) 提取物 (STE) 通过促进cGAMP合成,激活循环GMP-AMP合成酶 (cGAS) -STING通路. 这种机制有效地抑制了HBV复制,这表明STE是潜在的抗病毒疗法.

关键词:
这就是HBV HBV.索波拉基尼尼斯 (Sophora tonkinensis) 是一种的植物. [植物科] 植物科抗病毒反应的抗病毒反应.在cGAS-STING路径中.免疫学 免疫学 免疫学

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