后COVID-19肺部后果:表现,机制和治疗策略
Kai Xie1, Peipei Zhang1, Yan Li1
1Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Journal of thoracic disease
|October 29, 2025
概括
长期的COVID可能会导致长期的肺损伤,包括肺功能减弱和持续的呼吸道症状. 了解机制和探索肺部康复等治疗方法是改善COVID-19后肺部瘤患者康复的关键.
科学领域:
- 肺部病理学 肺部病理学
- 传染性疾病 传染性疾病
- 病理生理学 病理生理学
背景情况:
- 冠状病毒疾病2019 (COVID-19) 可能导致长期健康问题,称为长期COVID或COVID-19后状态.
- 肺部连续病例很常见,并显著影响患者的生活质量.
研究的目的:
- 审查临床表现,潜在机制,以及COVID-19后肺部瘤的潜在治疗方法.
- 巩固当前关于COVID-19的长期呼吸系统影响的知识.
主要方法:
- 关于COVID-19后肺部后果研究的文献综述.
- 分析报告的症状,肺功能测试和成像发现.
- 探索拟议的病理生理机制和治疗策略.
主要成果:
- 常见的症状包括疲劳,呼吸不全和睡眠障碍;呼吸系统症状包括咳,缺氧和运动能力下降.
- 肺部扩散能力受损和胸部CT上的异常 (地面玻璃不透明,纤维变化,空气捕获) 是常见的.
- 潜在的机制包括肺纤维化,慢性炎症,免疫失调,凝血问题和持续的病毒感染.
结论:
- 后COVID-19肺部后遗症呈现出各种症状和成像发现,由复杂的机制驱动.
- 目前的管理包括疫苗接种,肺部康复和药物干预.
- 进一步了解康复轨迹和机制对于有效的患者管理至关重要.
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