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肺移植期间大规模输血的预测,发生率和结果

Ping Gao¹, Shui Yu¹, Xinchen Tao¹

¹Department of Anesthesiology, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China.

Journal of thoracic disease

|October 29, 2025

概括

肺移植期间大量输血与更糟糕的结果有关. 低BMI和低血红素预测需要大量输血,突出了手术前优化机会.

科学领域:

心血管和呼吸系统医学
移植手术移植手术
关键护理医学关键护理医学

背景情况:

肺移植 (LT) 期间的大规模输血 (MT) 可以显著增加外科手术后并发症和死亡率.
有限的研究存在于与LT中MT相关的风险因素和预后.
了解MT发生率,风险因素和结果对于改善LT患者护理至关重要.

研究的目的:

为了调查肺移植期间大量输血的发生率.
确定与LT患者大规模输血相关的术前风险因素.
评估大规模输血对LT的结果和预后影响.

主要方法:

从2020年2月到2022年3月,对成年LT患者的回顾性分析.
定义MT作为在LT期间给予≥10个红细胞单位 (RBCs).
逻辑回归用于风险因素分析,卡普兰-梅尔用于生存,以及Cox分析用于预后因素.

主要成果:

10.4%的LT患者 (15/144) 接受了MT;低BMI和手术前血红素是独立的危险因素.
经过长时间的手术,MT组的输血量增加,尿量减少,CRRT和30天死亡率更高.
MT是30天死亡率的独立预测因子 (HR=5.13,P<0.001).

结论:

肺移植期间的大规模输血是相对常见的,并与不良结果相关.
低BMI和手术前血红素值是MT的重要预测因素.
在手术前优化营养状况和纠正贫血可能会减少MT并改善LT结果.

关键词:

肺移植 (LT) 是一种肺移植手术.身体质量指数 (BMI) 是指身体质量指数.大规模输血 (MT)有关风险因素的风险因素.

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