相关实验视频

Updated: Jul 13, 2026

Cell Population Analyses During Skin Carcinogenesis

Cell Population Analyses During Skin Carcinogenesis

Published on: August 21, 2013

来自荷兰皮细胞癌协作组织 (DKCC) 的高级皮肤状细胞癌的纵向数据:全国实体数据库研究:全国实体数据库研究

Loes M Hollestein^1,2, Celeste J Eggermont¹, Marieke W J Louwman²

¹Department of Dermatology, Erasmus MC Cancer Institute, University Medical Center, Rotterdam, the Netherlands.

The Lancet regional health. Europe

|October 29, 2025

概括

荷兰皮细胞癌协作组织 (DKCC) 建立了一个全国性的高级皮肤状细胞癌 (CSCC) 数据库. 该注册表提供了关键的流行病学数据,以改善患者护理和这种常见癌症的临床指南.

科学领域:

在瘤学瘤学.
流行病学流行病学
癌症研究癌症研究

背景情况:

皮肤状细胞癌 (CSCC) 是一种普遍存在的癌症,但全面的流行病学数据,特别是晚期癌症,仍然有限.
了解晚期CSCC的流行病学对于识别结果差异和加强患者管理至关重要.
数据稀缺,需要建立强大的注册表,以支持临床决策和研究.

研究的目的:

建立一个高质量的全国性流行病学数据库,用于荷兰先进的CSCC.
收集局部晚期,复发性和转移性CSCC (高级CSCC) 的纵向数据.
为改善高级CSCC的临床指南和患者护理提供必要的数据.

主要方法:

荷兰皮细胞癌协作 (DKCC) 旨在作为一个全国性的纵向数据库.
从荷兰全国病理数据库 (Palga) 中,使用经过验证的算法识别了高级的CSCC病例.
关于瘤特征,诊断,疾病进展和治疗的数据被手动记录在选定的患者身上,并与其他国家注册表联系起来.

主要成果:

在2021年,估计所有CSCC诊断的8.0%是局部先进的.
在2021-2022年,DKCC注册了920名患有晚期CSCC的患者.
显著比例的转移患者有先前的复发,显著比例的转移发作没有接受治疗.

结论:

DKCC代表了先进的CSCC的第一个全国纵向数据源.
在全球范围内,DKCC的方法可以作为建立类似的罕见癌症注册表的典范.
来自DKCC的数据对于加强临床指南和优化高级CSCC患者护理至关重要.

关键词:

皮肤状细胞癌瘤流行病学流行病学局部发达的皮肤状细胞癌.转移转移转移转移全国范围的癌症登记册.复发情况复发情况

更多相关视频

Establishment of a Clinic-based Biorepository

Establishment of a Clinic-based Biorepository

Published on: May 29, 2017

Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition

Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition

Published on: August 18, 2022

相关概念视频

Skin Cancer

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...

Cancer Survival Analysis

Cancer Survival Analysis

Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...