健康的饮食模式和卵巢癌的风险和生存率:一个系统的审查和元分析
Yiyi Xu1, Jiner Chen1, Ke Zhao1
1Department of Obstetrics and Gynecology, The Sixth People's Hospital of Zhuji, Zhuji, Zhejiang, China.
Frontiers in nutrition
|October 29, 2025
概括
坚持健康的饮食模式可以显著降低卵巢癌的风险,并提高生存率. 这一元分析证实了健康饮食对抗卵巢癌的保护作用.
科学领域:
- 在瘤学瘤学.
- 营养科学 营养科学
- 流行病学 流行病学
背景情况:
- 有限且不一致的研究存在于健康饮食模式和卵巢癌风险/生存率.
- 为了解决这一知识差距,进行了全面的系统审查和元分析.
研究的目的:
- 分析现有的关于健康饮食模式与卵巢癌风险之间的关联的文献.
- 研究健康饮食模式与卵巢癌存活率之间的联系.
主要方法:
- 对PubMed,Web of Science,Scopus和CNKI研究的系统审查和元分析,截至2024年10月.
- 聚合相对风险 (RRs) 和95%置信区间 (CI) 用随机效应或固定效应模型计算.
- 包括16项研究,超过615,000名参与者,分析卵巢癌风险,存活率和死亡率.
主要成果:
- 对健康饮食模式的高度坚持与卵巢癌的风险降低有关 (RR = 0.91; 95% CI: 0.85-0.98).
- 健康的饮食模式与改善卵巢癌存活率有关 (RR = 0.85;95% CI:0.76-0.95).
- 在健康饮食得分中的每一个标准偏差增量,都将卵巢癌死亡率降低14% (RR = 0.86;95%CI:0.81-0.91).
结论:
- 对健康饮食模式的高度坚持与减少卵巢癌风险和改善生存率有关.
- 研究结果表明,健康饮食在卵巢癌中起着保护作用.
- 建议进行进一步的大规模前性研究,以加强这些结论.
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