Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关实验视频

Updated: Jan 13, 2026

Thermal Imaging to Study Stress Non-invasively in Unrestrained Birds
10:07

Thermal Imaging to Study Stress Non-invasively in Unrestrained Birds

Published on: November 6, 2015

14.0K

ForSys:从时间间隔显微镜的非侵入性压力推断.

Augusto Borges1,2, Jerónimo R Miranda-Rodríguez1,3, Alberto S Ceccarelli4,5

  • 1Unit Sensory Biology and Organogenesis, Helmholtz Zentrum München, Munich, Germany.

iScience
|October 29, 2025
PubMed
概括

相关概念视频

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Protocol for inferring mechanical stresses in tissues using ForSys, an open-source Python tool.

STAR protocols·2026
Same author

Single-cell morphodynamics predict cell fate decisions during mucociliary epithelial differentiation.

Molecular systems biology·2026
Same author

Local control of cellular proliferation underlies neuromast regeneration in zebrafish.

Journal of theoretical biology·2026
Same author

Ethylene modulates cell wall mechanics for root responses to compaction.

Nature·2025
Same author

Single-cell morphodynamics predict cell fate decisions during mucociliary epithelial differentiation.

bioRxiv : the preprint server for biology·2025
Same author

Effects of n-3 Long-Chain Polyunsaturated Fatty Acid and Vitamin D Supplementation on Transcriptional Profiles of Human Lung Organoids.

Metabolites·2025
Same journal

Advancing microalgae biomass cultivation for an integrated sustainable wastewater treatment and resource recovery.

iScience·2026
Same journal

Corrigendum to "Human adipose ECM alleviates radiation-induced skin fibrosis via endothelial cell-mediated M2 macrophage polarization" [iScience, Volume 26, Issue 9 (2023) 107660].

iScience·2026
Same journal

High-definition transcranial direct current stimulation enhances exercise-induced hypoalgesia in patients with chronic low back pain.

iScience·2026
Same journal

From pre-tumor to tumor: Decoding the endoscopic-pathologic spectrum of neoplastic lesions in autoimmune gastritis.

iScience·2026
Same journal

Corrigendum to "A cobalt-aluminium layered double hydroxide with a nickel core-shell structure nanocomposite for supercapacitor applications" [iScience, 28 (2025) 111672].

iScience·2026
Same journal

Repurposing primaquine diphosphate for imatinib-resistant chronic myeloid leukemia via targeting BCR-ABL and Wnt/β-catenin pathway.

iScience·2026
查看所有相关文章
此摘要是机器生成的。

ForSys软件使用显微镜估计组织发育期间的细胞应力. 它揭示了驱动生物体细胞行为和组织模式的机械力量.

科学领域:

  • 生物物理学的生物物理.
  • 发展生物学 发展生物学
  • 计算生物学 计算生物学

背景情况:

  • 机械力对组织发育和再生至关重要.
  • 在体内测量这些力量是非常具有挑战性的.
  • 现有的压力推断算法很难将组织动态纳入.

研究的目的:

  • 介绍ForSys,一种基于Python的新软件,用于推断细胞间压力和细胞内压力.
  • 从时间间隔显微镜数据中启用动态应力推断.
  • 在组织形态发生过程中分析机械力量的时空模式.

主要方法:

  • 开发了一个多功能软件工具ForSys.
  • 使用模拟和实验数据验证了ForSys.
  • 应用ForSys对斑马鱼的横向线原始迁移和神经巨发育.
  • 与斐济集成的ForSys提供了图形用户界面,并接受了EPySeg和Cellpose的细分.

主要成果:

  • ForSys成功地推断出时间缩短显微镜的细胞间应力和细胞内压力.
  • 在斑马鱼中揭示了细胞圆形化前的线粒分裂过程中增加的压力.
  • 准确地预测了上皮层红色生成的开始.
关键词:
光学成像技术的使用.

更多相关视频

Time-Lapse Video Microscopy for Assessment of EYFP-Parkin Aggregation as a Marker for Cellular Mitophagy
09:29

Time-Lapse Video Microscopy for Assessment of EYFP-Parkin Aggregation as a Marker for Cellular Mitophagy

Published on: May 4, 2016

7.5K
Temporal Quantification of MAPK Induced Expression in Single Yeast Cells
07:59

Temporal Quantification of MAPK Induced Expression in Single Yeast Cells

Published on: October 4, 2013

8.9K

相关实验视频

Last Updated: Jan 13, 2026

Thermal Imaging to Study Stress Non-invasively in Unrestrained Birds
10:07

Thermal Imaging to Study Stress Non-invasively in Unrestrained Birds

Published on: November 6, 2015

14.0K
Time-Lapse Video Microscopy for Assessment of EYFP-Parkin Aggregation as a Marker for Cellular Mitophagy
09:29

Time-Lapse Video Microscopy for Assessment of EYFP-Parkin Aggregation as a Marker for Cellular Mitophagy

Published on: May 4, 2016

7.5K
Temporal Quantification of MAPK Induced Expression in Single Yeast Cells
07:59

Temporal Quantification of MAPK Induced Expression in Single Yeast Cells

Published on: October 4, 2013

8.9K
  • 在神经巨发育中发现了与细胞类型特定粘附相关的机械不对称性.

    • 结论:

    • ForSys提供了一种强大而通用的工具,用于在体内分析机械力.
    • 该软件有助于研究机械力如何调节组织形态发生和再生.
    • 实现动态应激推断,推进发育生物学中的生物物理分析领域.