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更高的牙损伤率和心血管疾病风险增加

Catherine Roberts¹, Dylan J Baxter¹, Dobrawa Napierala¹

¹Department of Oral and Craniofacial Sciences, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA, United States.

Frontiers in oral health

|October 29, 2025

概括

以腐烂的缺失和填充牙 (DMFT) 和表面 (DMFS) 来衡量较高的牙损伤率,独立地与心血管疾病有关. 这表明牙健康可能会影响传统风险因素之外的心脏健康.

科学领域:

口腔卫生流行病学口腔卫生流行病学
心血管疾病研究研究
公共卫生公共卫生

背景情况:

在考虑共享风险因素时,关于牙损伤和心血管疾病 (CVD) 之间的关联存在不确定的流行病学证据.
牙腐烂的定量指数,如腐烂的缺失和填充的表面/牙 (DMFS/DMFT),需要进一步调查它们与心血管疾病的独立关联.

研究的目的:

确定牙损伤 (DMFS/DMFT) 和心血管疾病的定量指数之间的独立关联.
在两个不同的大规模牙科和医疗数据集中分析这些关联,控制传统的风险因素.

主要方法:

使用牙科登记和DNA存储库 (DRDR) 和国家健康和营养检查调查 (NHANES) 的数据进行横截面分析.
采用多重回归模型来评估DMFS/DMFT和心血管疾病之间的关联,并根据年龄,性别,吸烟,种族,收入和牙周状况等共变量进行调整.
使用R软件和STATA进行了统计分析,并对多次测试进行了调整.

主要成果:

与NHANES参与者相比,DRDR数据集中的参与者报告的心血管疾病史 (23.97%) 和DMFT得分 (19.58) 比NHANES参与者 (18.06%心血管疾病,14.78 DMFT) 高.
在调整了混因子后,DMFS在DRDR人群中显示出与心血管疾病的显著关联 (p < 0.006).
在NHANES数据集中,DMFT与心血管疾病有显著的关联 (p < 0.0001),即使考虑到多种风险因素和牙周健康指标.

结论:

牙损的更高患病率独立地与患有心血管疾病病史的可能性增加有关.
这些发现突出了口腔健康状况和心血管健康之间的潜在联系,独立于已确定的风险因素.

关键词:

在DMFS指数中,DMFS是指数.DMFT (腐烂的缺失和填充的牙)尼汉斯 (NHANES) 是一个名人.心血管疾病心血管疾病牙腐烂是指牙的腐烂.

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