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Updated: Jan 13, 2026

Visualizing Lung Cellular Adaptations during Combined Ozone and LPS Induced Murine Acute Lung Injury
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Published on: March 21, 2021

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线粒体功能障碍触发了Zbp1-介导的亡和炎症在急性肺损伤

Mi Zhou1, Yuehan Li1, Yinying Ren1

  • 1Department of Pediatric Respiratory Medicine; National Clinical Research Center for Child Health and Disorders; Ministry of Education Key Laboratory of Child Development and Disorders; China International Science and Technology Cooperation Base of Child Development and Critical Disorders; Chongqing Engineering Research Center of Stem Cell Therapy, Children's Hospital of Chongqing Medical University, Chongqing, China.

Biomolecules & biomedicine
|October 29, 2025
PubMed
概括

肺细胞中的线粒体损伤通过指蛋白1 (Zbp1) 触发亡,导致急性肺损伤 (ALI) 的炎症. 准线粒体的活性氧物种 (mtROS) 可以减少亡并防止ALI.

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