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Updated: Jan 13, 2026

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结构模型导向的重编程使甲和甲合成酶的功能互换成为可能.

Li Zhang1, Yinghan Chen2, Yan Wang1

  • 1State Key Laboratory of Pharmaceutical Biotechnology, Institute of Functional Biomolecules, Department of Neurology, Nanjing Drum Tower Hospital, Chemistry and Biomedicine Innovation Center (ChemBIC), School of Life Sciences, Nanjing University, Nanjing, 210023, China.

Angewandte Chemie (International ed. in English)
|October 29, 2025
PubMed
概括

研究人员确定了细菌烯合成酶的phomactatriene和verticillene,揭示了一个共享的生物合成途径. 这些酶的工程设计为自然产品合成中的生物技术应用提供了潜力.

关键词:
酶重新设计的方法分子动力学分子动力学这种类型的物质是phomactatriene.烯合成酶的使用方法垂直烯是一种垂直烯.

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