两极性谱系障碍退伍军人的神经认知功能和冲动性:自杀未遂者与未尝试者
Chi C Chan1,2,3, Sharon Alter1,2, Isabelle Baptista1,2
1VISN 2 Mental Illness Research, Education, and Clinical Center, James J. Peters VA Medical Center, Bronx, New York.
The Journal of clinical psychiatry
|October 29, 2025
概括
试图自杀的双相情感障碍 (BD) 的退伍军人与没有尝试自杀的退伍军人相比,表现出更差的工作记忆和语言学习. 神经认知缺陷,特别是在工作记忆中,可能会在这个人群中驱动侵略和自杀行为.
科学领域:
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
- 退伍军人健康 退伍军人的健康
背景情况:
- 退伍军人身份和双相情感障碍 (BD) 是自杀的重要危险因素.
- 神经认知功能障碍和冲动性与自杀行为有关.
研究的目的:
- 为了检查神经认知功能障碍和冲动性与BD的退伍军人中自杀企图的相关性.
- 研究退伍军人的特定认知缺陷和自杀行为之间的关系.
主要方法:
- 包括29名BD和自杀未遂史的退伍军人 (BD/SA+),33名BD没有自杀未遂史的退伍军人 (BD/SA-),以及22名健康控制退伍军人 (HC).
- 进行认知评估 (MATRICS共识认知电池) 和冲动性/侵略性尺度 (巴拉特冲动性尺度等). ) 的情况.
主要成果:
- 与BD/SA-和HC组相比,BD/SA+组在工作记忆和口头学习方面表现更差.
- 在调整情绪症状后,BD/SA+患者的工作记忆缺陷仍然显著.
- BD/SA+组在冲动性和预谋性攻击方面表现出更高的分数.
结论:
- 工作记忆较差与BD退伍军人的自杀企图有关,独立于抑郁症状.
- 在这个人群中,口头学习障碍可能受到抑郁症的影响.
- 神经认知功能障碍可能会导致攻击性,导致自杀行为,并可以为风险检测和干预策略提供信息.
更多相关视频
相关概念视频
Bipolar Disorder
584
Bipolar disorder is a chronic mental health condition marked by significant mood fluctuations, including episodes of mania and depression. Elevated energy levels, heightened mood or irritability, impulsive behavior, reduced sleep needs, rapid speech, racing thoughts, inflated self-esteem, and distractibility characterize mania. Individuals with bipolar disorder often alternate between depressive and manic states, with periods of emotional stability lasting an average of six months to a year.
584
Borderline Personality Disorder
473
Borderline Personality Disorder is a complex and multifaceted mental health condition characterized by pervasive instability in interpersonal relationships, self-image, emotions, and impulse control. This instability manifests in extreme emotional reactions, fear of abandonment, and self-destructive behaviors. The disorder significantly impacts daily functioning, often leading to distress in both personal and professional domains.
Genetic and Environmental Contributions
Borderline Personality...
Genetic and Environmental Contributions
Borderline Personality...
473
Depressive Disorders: Etiology
406
Depressive disorders result from a complex interplay of biological, psychological, and sociocultural factors, each contributing uniquely to the development and persistence of the condition. Understanding these factors provides critical insight into the multifaceted nature of depression.
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
406


