Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Phylogeny01:23

Phylogeny

56.7K
Phylogeny is concerned with the evolutionary diversification of organisms or groups of organisms. A group of organisms with a name is called a taxon (singular). Taxa (plural) can span different levels of the evolutionary hierarchy. For instance, the group containing all birds is a taxon (comprising the class Aves), and the group of all species of daisies (the genus Bellis) is a taxon. Phylogenies can likewise include just one genus (i.e., depict species relationships) or span an entire kingdom.
56.7K
Evolutionary Relationships through Genome Comparisons02:54

Evolutionary Relationships through Genome Comparisons

6.8K
Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...
6.8K
Phylogenetic Trees03:21

Phylogenetic Trees

49.2K
Phylogenetic trees come in many forms. It matters in which sequence the organisms are arranged from the bottom to the top of the tree, but the branches can rotate at their nodes without altering the information. The lines connecting individual nodes can be straight, angled, or even curved.
49.2K
Ribosome Profiling02:24

Ribosome Profiling

4.1K
Ribosome profiling or ribo-sequencing is a deep sequencing technique that produces a snapshot of active translation in a cell. It selectively sequences the mRNAs protected by ribosomes to get an insight into a cell’s translation landscape at any given point in time.
Applications of ribosome profiling
Ribosome profiling has many applications, including in vivo monitoring of translation inside a particular organ or tissue type and quantifying new protein synthesis levels.
The technique...
4.1K
Comparing Mitochondrial, Chloroplast, and Prokaryotic Genomes02:16

Comparing Mitochondrial, Chloroplast, and Prokaryotic Genomes

15.0K
The present-day mitochondrial and chloroplast genomes have retained some of the characteristics of their ancestral prokaryotes and also have acquired new attributes during their evolution within eukaryotic cells. Like prokaryotic genomes, mitochondrial and chloroplast genomes neither bind with histone-like proteins nor show complex packaging into chromosome-like structures, as observed in eukaryotes. Unlike mitotic cell divisions observed in eukaryotic cells, mitochondria and chloroplasts...
15.0K
Pedigree Analysis01:35

Pedigree Analysis

88.8K
Overview
88.8K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

The extraordinary satellitome diversity of freshwater crayfish: a driver of genome evolution.

Mobile DNA·2026
Same author

OMAnnotator: a novel approach to building an annotated consensus genome sequence.

Bioinformatics advances·2026
Same author

EdgeHOG: a method for fine-grained ancestral gene order inference at large scale.

Nature ecology & evolution·2025
Same author

Characterisation of the noble crayfish immune response to oomycete-derived immunostimulants.

Fish & shellfish immunology·2025
Same author

Orthology inference at scale with FastOMA.

Nature methods·2025
Same author

New developments for the Quest for Orthologs benchmark service.

NAR genomics and bioinformatics·2024
Same journal

Sensing Underwater: Diversifying Selection, Convergent Evolution and Inactivation in Sensory Receptors' Genes of Aquatic Mammals.

Journal of molecular evolution·2026
Same journal

Synonymous Codons as Potential Contributors to Chromatin Stability and Gene Body Methylation in Plants.

Journal of molecular evolution·2026
Same journal

Convergent Functional Genomic Evolution Underlying Repeated Freshwater Colonization in Cetaceans.

Journal of molecular evolution·2026
Same journal

Conditions Enabling the Persistence of Cooperating Synthetase, Ligase, and Mutation-Inhibitor Catalytic Polymers.

Journal of molecular evolution·2026
Same journal

Lineage-Specific Diversification of Nucleoporin Nup98 Genes in Ciliates and Its Evolutionary Implications for the Nuclear Dualism.

Journal of molecular evolution·2026
Same journal

Mitochondrial Genome Evolution: The Influence of Partitioning, Calibration, and Gene Heterogeneity on Pleurodontan Substitution Rates.

Journal of molecular evolution·2026
查看所有相关文章

相关实验视频

Updated: Jan 13, 2026

A Practical Guide to Phylogenetics for Nonexperts
12:00

A Practical Guide to Phylogenetics for Nonexperts

Published on: February 5, 2014

36.0K

Profylo:一个Python软件包,用于对遗传学资料进行比较和分析.

Martin Schoenstein1, Pauline Mermillod2, Arnaud Kress2,3

  • 1Complex Systems and Translational Bioinformatics (CSTB), Department of Computer Science, UMR7357 ICube, University of Strasbourg, CNRS, Centre de Recherche en Biomédecine de Strasbourg, Rue Eugène Boeckel 1, 67000, Strasbourg, France. martin.schoenstein@etu.unistra.fr.

Journal of molecular evolution
|October 29, 2025
PubMed
概括
此摘要是机器生成的。

Profylo是一个开源的Python工具包,用于遗传学分析,通过共同进化模式实现基因功能推断. 它提供了多种比较方法和聚类算法,用于分析基因存在缺失数据.

关键词:
共同进化的共同进化进行比较的基因组学.遗传学概要编制 遗传学概要编制在Python中使用Python包.

更多相关视频

Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations
08:03

Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations

Published on: December 7, 2021

2.7K
An Integrated Approach for Microprotein Identification and Sequence Analysis
09:37

An Integrated Approach for Microprotein Identification and Sequence Analysis

Published on: July 12, 2022

3.9K

相关实验视频

Last Updated: Jan 13, 2026

A Practical Guide to Phylogenetics for Nonexperts
12:00

A Practical Guide to Phylogenetics for Nonexperts

Published on: February 5, 2014

36.0K
Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations
08:03

Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations

Published on: December 7, 2021

2.7K
An Integrated Approach for Microprotein Identification and Sequence Analysis
09:37

An Integrated Approach for Microprotein Identification and Sequence Analysis

Published on: July 12, 2022

3.9K

科学领域:

  • 生物信息学是一种生物信息学.
  • 计算生物学 计算生物学
  • 基因组学就是基因组学.

背景情况:

  • 遗传学概况分析基因正统存在缺失模式,通过共同进化推断功能关联.
  • 现有的遗传学分析方法缺乏易于使用的软件实现.
  • 需要可访问的工具来构建,比较和分析用于基因功能预测的遗传学资料.

研究的目的:

  • 介绍Profylo,一个开源的Python软件包用于遗传学分析.
  • 为了提供一个全面的工具包,多种方法用于基因谱的资料比较和共同进化的基因集群的识别.
  • 在预测人类基因功能关系方面对实施的方法的性能进行基准测试.

主要方法:

  • Profylo实施了七种不同的方法来比较家族遗传资料.
  • 该工具包包括四种算法,用于识别共同进化的基因集群.
  • 分析工具,包括可视化功能,都集成在Profylo包中.

主要成果:

  • 该研究使用各种数据集对Profylo用于预测人类基因之间的功能关系的方法进行了基准测试.
  • 通过分析人类基因组中所有蛋白质编码基因的存在-缺失的案例研究来证明Profylo的实用性.
  • 开源的Python 3.0软件包在GitHub上可供公众访问和使用.

结论:

  • Profylo提供了一种多功能且易于使用的解决方案,用于遗传学分析分析.
  • 该工具包促进了对基因共同进化模式的探索,用于功能推断.
  • Profylo支持计算生物学和基因组学研究人员,提供用于基因功能预测的实用工具.