对于评估全身麻醉患者的体积响应度,对状动脉纠正流量时间和中风体积变化的变化进行比较:一项前性观察性研究
Yongyong Yang1,2, Min Li3, Chenlong Yang1,2
1Department of Anesthesiology, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, No. 999, Huashan Rd, 350212, Fuzhou, China.
Journal of clinical monitoring and computing
|October 29, 2025
概括
校正动脉流量时间 (ΔFTc) 的超声波测量可以准确地评估通风患者的液体反应. 这种非侵入性方法显示出更大的临床适用性比侵入性中风体积变化 (ΔSVV) 引导液体的管理.
科学领域:
- 麻醉学和重症监护医学
- 心血管生理学心血管生理学
- 护理中心超声波检查
背景情况:
- 在机械通风下评估手术患者的液体反应能力至关重要,但在非侵入性方法中具有挑战性.
- 准确识别将从液体管理中受益的患者是优化血液动力学的关键.
- 目前用于预测流体响应性的非侵入性床边方法存在局限性.
研究的目的:
- 为了比较非侵入性超声波测量校正动脉流量时间 (ΔFTc) 的变化与侵入性中风体积变化 (ΔSVV) 的有效性,评估流体响应.
- 在机械通风患者中,评估 ΔFTc 与 ΔSVV 相比的诊断准确性和临床适用性.
- 为了确定 ΔFTc 和 ΔSVV 的最佳切割值,用于预测流体响应.
主要方法:
- 一项前性观察性研究,涉及91名在全身麻醉和机械通风下接受选择性腹部手术的患者.
- 非侵入性床边超声波用于测量 ΔFTc,而侵入性血液动力学监测评估 ΔSVV 在液体注射之前和之后.
- 流体反应者被定义为流体挑战后中风体积增加≥10%.
主要成果:
- 54%的患者被确定为流体反应者.
- ΔFTc (AUC 0.85) 和 ΔSVV (AUC 0.84) 在预测流体响应性方面都表现出很高的准确性.
- 与ΔSVV (1-3%) 相比,ΔFTc显示了较窄的灰色区域 (7-12 ms),这表明了更精确的评估.
- ΔFTc 的最佳切割值为 7.03 ms (灵敏度为 91.5%,特异性为 69.8%),而 ΔSVV 的最佳切割值为 2.85% (灵敏度为 95.6%,特异性为 72.6%).
结论:
- ΔFTc 和 ΔSVV 都是机械通风患者流体反应的可靠指标.
- 非侵入性超声波测量 ΔFTc 为评估体积响应性提供了准确和临床适用的替代方案.
- 通过超声波测量 ΔFTc 为指导手术患者流体治疗提供了宝贵的床边工具.
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