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Updated: Jun 7, 2026

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Pt-seq揭示了基于的药物的基因组结合模式

Chuyun Shao1,2, Mingyang Li1,3, Liuyi Liu4

  • 1State Key Laboratory of Gene Function and Modulation Research, School of Life Sciences, Peking University, Beijing, China.

Science advances
|October 29, 2025
PubMed
概括

基于的药物 (Pt药物) 对于癌症化疗至关重要. 新的Pt-seq技术绘制了全基因组的Pt-DNA引导图,揭示了关键的结合部位,并改善了对药物耐药性和疗效的理解.

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Peptide Identification Using Tandem Mass Spectrometry01:33

Peptide Identification Using Tandem Mass Spectrometry

Tandem mass spectrometry, also known as MS/MS or MS2, is an analytical technique that employs two mass analyzers. Essentially it is a series of mass spectrometers that helps isolate a particular biomolecule and then helps study its chemical properties.
This technique helps gather information regarding the protein from which the peptide was obtained and to study the peptides’ amino acid sequence. Identifying peptides from a complex mixture is an important component of the growing field of...