相关实验视频

Updated: Jan 13, 2026

Author Spotlight: Advancements in Multiplex Detection of Respiratory Viruses

Author Spotlight: Advancements in Multiplex Detection of Respiratory Viruses

Published on: November 10, 2023

针对2025-2026年Covid-19,RSV和流感疫苗的最新证据

Jake Scott¹, Michael S Abers², Harleen K Marwah³

¹Division of Infectious Diseases and Geographic Medicine, Stanford University School of Medicine, Stanford, CA.

The New England journal of medicine

|October 29, 2025

概括

独立证据证实了COVID-19,RSV和流感疫苗接种在2025-2026赛季的安全性和有效性. 这一审查为疫苗咨询决策提供了关键数据.

科学领域:

免疫学免疫学免疫学
公共卫生公共卫生
流行病学流行病学

背景情况:

疫苗咨询过程中出现的干扰需要对呼吸道病毒免疫接种进行独立的证据审查.
2025-2026赛季需要更新关于COVID-19,RSV和流感疫苗的指导方针.

研究的目的:

系统地审查美国授权的针对COVID-19,RSV和流感疫苗的疗效,有效性和安全性.
为即将到来的2025-2026年呼吸道病毒季节提供免疫指南.

主要方法:

对COVID-19,RSV和流感疫苗的研究进行系统审查.
在PubMed/MEDLINE,Embase和Web of Science中搜索了来自2023-2024年ACIP证据推审查的最新数据.
评估了疫苗的疗效,对住院和临床终点的有效性,以及安全性概况.

主要成果:

COVID-19 mRNA疫苗在成年人中对住院治疗的有效率为46-50%,在免疫功能低下的成年人中为37%.
接种RSV疫苗 (孕产妇,尼尔塞维马布,成年人) 显示,抗住院治疗的有效率高于68%.
流感疫苗在成年人中有效率为48%,在儿童中有效率为67%,防止住院.
安全性概况与先前的数据一致,并注意到罕见的不良事件,如心肌炎和吉兰-巴雷综合征.

结论:

目前的同行评审证据支持COVID-19,RSV和流感免疫的持续安全性和有效性.
这种证据基础对于指导2025-2026免疫接种季节的公共卫生建议至关重要.

更多相关视频

Generation, Amplification, and Titration of Recombinant Respiratory Syncytial Viruses

Generation, Amplification, and Titration of Recombinant Respiratory Syncytial Viruses

Published on: April 4, 2019

A Luciferase-fluorescent Reporter Influenza Virus for Live Imaging and Quantification of Viral Infection

A Luciferase-fluorescent Reporter Influenza Virus for Live Imaging and Quantification of Viral Infection

Published on: August 14, 2019

相关概念视频

Vaccinations

Vaccinations

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...

Viral Recombination

Viral Recombination

Cells are sometimes infected by more than one virus at once. When two viruses disassemble to expose their genomes for replication in the same cell, similar regions of their genomes can pair together and exchange sequences in a process called recombination. Alternatively, viruses with segmented genomes can swap segments in a process called reassortment.

Viral Mutations

Viral Mutations

A mutation is a change in the sequence of bases of DNA or RNA in a genome. Some mutations occur during replication of the genome due to errors made by the polymerase enzymes that replicate DNA or RNA. Unlike DNA polymerase, RNA polymerase is prone to errors because it is not capable of “proofreading” its work. Viruses with RNA-based genomes, like HIV, therefore accrue mutations faster than viruses with DNA-based genomes. Because mutation and recombination provide the raw material...