结核相关的周围假肢关节感染:报告了来自单一中心的11例病例
Arzu Nazli1, Ahmad Nejat Ghaffari1, Muammer Celik1
1Department of Infectious Diseases and Clinical Microbiology, Dokuz Eylul University Faculty of Medicine, 35330 Balçova/İzmir, Türkiye.
Diagnostic microbiology and infectious disease
|October 29, 2025
概括
结核相关的周围假肢关节感染 (TB-PJI) 诊断具有挑战性,但可治疗. 及时诊断和长期的抗结核病治疗与手术修复为TB-PJI提供了很好的结果.
科学领域:
- 整形外科手术 整形外科手术
- 传染性疾病 传染性疾病
- 微生物学 微生物学
背景情况:
- 结核相关的周围假肢关节感染 (TB-PJI) 是关节整形术后的一种罕见但严重的并发症.
- 由于非特异性症状和负面文化,诊断往往会延迟.
研究的目的:
- 分析结核相关的周围假肢关节感染的临床特征,诊断方法和治疗结果.
- 为TB-PJI提出一个诊断和管理算法.
主要方法:
- 追溯分析2000年至2025年培养确认的Mycobacterium结核病PJI病例.
- 收集人口统计,临床,微生物学,病理学和手术数据.
- 通过患者采访和医院记录评估结果.
主要成果:
- 确定了11名膝盖或部结核病-PJI患者.
- 所有病例均为M.结核病的培养阳性;GeneXpert MTB/RIF在所有测试中呈阳性.
- 组织病理学显示颗粒状炎症;10-14个月的抗结核治疗和两阶段的修订导致大多数患者成功地重新植入假肢,没有复发.
结论:
- 在耐火假肢感染中必须考虑TB-PJI,特别是在流行地区.
- 综合诊断工作,包括真菌菌培养,分子检测和组织病理学是至关重要的.
- 长期的抗结核病治疗和两阶段修复手术表明结核病-PJI的优秀结果.
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