没有的即时植入物的结果具有较低的初级稳定性
Eun-Ji Jang1, Jae-An Park1, Seung-Hoon Cha1
1Departments of Oral and Maxillofacial Surgery, Inje University Sanggye Paik Hospital, Inje University College of Medicine, Seoul, Korea.
Journal of the Korean Association of Oral and Maxillofacial Surgeons
|October 29, 2025
概括
立即放置的牙植入物具有较低的初级稳定性,证明了成功的骨整合和长期存活. 这项研究强调了即使初始植入物稳定系数 (ISQ) 值低于55的情况,也有可能产生有利的结果.
科学领域:
- 牙科 牙科是指牙科的专业.
- 口腔植入物学口腔植入物学
- 生物材料是一种生物材料.
背景情况:
- 评估具有初级稳定性损害的牙科植入物的预后对于可预测的治疗结果至关重要.
- 由插入扭矩和植入器稳定率 (ISQ) 定义的低初级稳定性,在立即植入器放置时提出了挑战.
- 喷砂,大粒,酸蚀刻 (SLAA) 植入物表面通常用于现代植入物学.
研究的目的:
- 评估立即放置的牙植入物的长期预后和存活率,其初级稳定性较低或不存在.
- 确定最初稳定性较低的植入物是否可以成功实现骨质整合.
- 分析植入物稳定系数 (ISQ) 值从安置到假肢加载的变化.
主要方法:
- 一项回顾性研究涉及16名接受16种SLAA表面植入物具有低初级稳定性 (插入扭矩<10Ncm,初始ISQ<55) 的患者.
- 植入物是使用无手术技术进行的.
- 使用ISQ系统 (奥斯泰尔) 测量了植入物稳定性,在植入后立即和印记时 (植入后平均13周).
主要成果:
- 除了6例无法测量的初始ISQ外,初始平均ISQ为42.2±7.5,在打印时增加到68.7±7.6 (P<0.01).
- 在平均随访65.18个月后,观察到100%的植入物存活率.
- 显著改善的ISQ值表明,尽管最初的稳定性很低,但骨质整合成功.
结论:
- 立即放置的牙植入物具有很低或没有初级稳定性,可以成功实现骨质整合.
- 由于最初的初级稳定性较低,长期植入物存活不会受到影响.
- 临床方案可以调整,以适应即时的植入物放置,即使在非最佳初级稳定性的情况下.
相关概念视频
RNA Stability
Intact DNA strands can be found in fossils, while scientists sometimes struggle to keep RNA intact under laboratory conditions. The structural variations between RNA and DNA underlie the differences in their stability and longevity. Because DNA is double-stranded, it is inherently more stable. The single-stranded structure of RNA is less stable but also more flexible and can form weak internal bonds. Additionally, most RNAs in the cell are relatively short, while DNA can be up to 250 million...
mRNA Stability and Gene Expression
The structure and stability of mRNA molecules regulates gene expression, as mRNAs are a key step in the pathway from gene to protein. In eukaryotes, the half-life of mRNA varies from a few minutes up to several days. mRNA stability is essential in growth and development. The absence of the proteins regulating its stability, such as tristetraprolin in mice, can cause systemic issues, including bone marrow overgrowth, inflammation, and autoimmunity.
Cis-acting Elements involved in mRNA stability
Cis-acting Elements involved in mRNA stability
mRNA Stability and Gene Expression
The structure and stability of mRNA molecules regulates gene expression, as mRNAs are a key step in the pathway from gene to protein. In eukaryotes, the half-life of mRNA varies from a few minutes up to several days. mRNA stability is essential in growth and development. The absence of the proteins regulating its stability, such as tristetraprolin in mice, can cause systemic issues, including bone marrow overgrowth, inflammation, and autoimmunity.
Cis-acting Elements involved in mRNA stability
Cis-acting Elements involved in mRNA stability
Nondepolarizing (Competitive) Neuromuscular Blockers: Pharmacokinetics
All neuromuscular blocking agents are injected intravenously because they are poorly absorbed from the GI tract. Rapid onset is achieved with intravenous administration, although absorption is also adequate from an intramuscular injection. Since these agents are highly ionized, they do not readily penetrate cell membranes or cross the blood-brain barrier.
Instead, they are transported by the blood to different tissues. Muscles with a greater blood supply (arteries) and blood flow receive more...
Instead, they are transported by the blood to different tissues. Muscles with a greater blood supply (arteries) and blood flow receive more...
Drug Concentration Versus Time Correlation
The plasma drug concentration-time curve is a crucial tool in pharmacokinetics, representing the drug's concentration in plasma at different time intervals post-administration. This curve illustrates the drug's journey from absorption into the systemic circulation, distribution to body tissues, and eventual elimination through excretion or biotransformation.
Two pivotal parameters are the minimum effective concentration (MEC) and the minimum toxic concentration (MTC). The MEC is the lowest drug...
Two pivotal parameters are the minimum effective concentration (MEC) and the minimum toxic concentration (MTC). The MEC is the lowest drug...
Survival Tree
Survival trees are a non-parametric method used in survival analysis to model the relationship between a set of covariates and the time until an event of interest occurs, often referred to as the "time-to-event" or "survival time." This method is particularly useful when dealing with censored data, where the event has not occurred for some individuals by the end of the study period, or when the exact time of the event is unknown.
Building a Survival Tree
Constructing a survival tree begins...
Building a Survival Tree
Constructing a survival tree begins...


