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Updated: Jan 13, 2026

Reconstitution of Msp1 Extraction Activity with Fully Purified Components
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促进长寿的线粒体未折叠蛋白反应激活需要PeBoW复合物的元素

Adebanjo Adedoja1,2, Niclole Stuhr1,3, Yifei Zhou1

  • 1Department of Medicine, Diabetes Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, Massachusetts 02114, USA.

Genes & development
|October 29, 2025
PubMed
概括

降低电压依赖性离子通道-1 (VDAC-1) 功能通过激活线粒体展开蛋白反应 (UPR) 来延长寿命. PeBoW复合体调解了这种反应,对线粒体质量控制和寿命至关重要.

关键词:
这就是PeBoWW.线粒应激是一种压力.这就是 mitoUPRUPR 的意思.线粒体中的线粒体.

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