在资源有限的环境中,CT指导的高剂量速率间歇性支架疗法用于恶性肺病变
Simit Sapkota1, Subhas Pandit1, Sundar Suwal2
1Department of Clinical Oncology, Kathmandu Cancer Center, Bhaktapur 44800, Nepal.
Brachytherapy
|October 29, 2025
概括
高剂量间歇性支架疗法 (IBT) 提供了一个安全有效的治疗方法,用于低资源环境中的不可操作的肺病变. 这种微创手术方法在不适合手术的患者中实现了良好的局部控制.
科学领域:
- 在瘤学瘤学.
- 干预性放射学 干预性放射学
- 辐射瘤学 辐射瘤学
背景情况:
- 对不可手术的肺部疾病的非手术选择有限,特别是在低收入和中等收入国家 (LMICs).
- 在LMICs中,对立体体辐射疗法的访问受到限制,需要替代治疗.
研究的目的:
- 评估高剂量间歇性支架疗法 (IBT) 对LMIC中不可手术的肺病变的可行性和结果.
- 在资源有限的环境中展示CT引导IBT的技术和结果.
主要方法:
- 11名患有12个肺病变的患者在2022年6月至2024年6月期间接受了CT指导IBT.
- 一个多学科团队管理患者,治疗响应通过RECIST 1.1进行评估.
- 病变接受了20 Gy剂量,随访时间中位数为18.7个月.
主要成果:
- 在6个病变中观察到完全反应,在1个病变中观察到部分反应,在4个病变中观察到稳定的疾病.
- 当地对照率为75%,随访时间中位数为18.7个月.
- 轻微的并发症包括肺胸病 (27.3%),血液溶解 (27.3%),以及发烧 (18.2%).
结论:
- 用CT指导的IBT是一种有效,安全和最小侵入性治疗不可手术的肺病变的方法.
- IBT为不适合手术的患者提供了良好的局部控制,特别是在LMIC中.
- 这种技术提供了一个可行的替代方案,当先进的放射治疗是无法获得的.
关键词:
部的消去是指部的消去.支臂疗法是一种手臂疗法.高剂量速率的高剂量速率.间歇性支臂疗法 (英语:Interstitial brachytherapy) 是一种间歇性支臂疗法.肺癌是一种肺癌.转移 转移 转移 转移治疗结果的结果.更多相关视频
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